Results 111 to 120 of about 1,320,970 (304)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Properties and customization of sensor materials for biomedical applications. [PDF]

open access: yes, 2014
Low-power chemo- and biosensing devices capable of monitoring clinically important parameters in real time represent a great challenge in the analytical field as the issue of sensor calibration pertaining to keeping the response within an accurate ...
Aguilar   +343 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Consequences of Sheep Blood Used as Diluting Agent for The Magnetoviscous Effect in Biocompatible Ferrofluids

open access: yesApplied Rheology, 2015
Magnetic nanoparticles suspended in suitable carrier liquids can be adopted for use in biomedicine. For this to be achieved, the biocompatibility of these ferrofluids needs to be ascertained.
Nowak J., Nowak C., Odenbach S.
doaj   +1 more source

Selective laser sintering and its application in biomedical engineering [PDF]

open access: yes, 2011
Rapid prototyping (RP) technologies, which are based on computer-aided design and computer-aided manufacturing, are widely employed in traditional industries.
Duan, B, Wang, M
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Elastohydrodynamic lubrication and wear modelling of the knee joint replacements with surface topography

open access: yesBiosurface and Biotribology, 2018
This numerical study predicted wear of lubricated total knee replacements with the existing of textured surface and the possibility of surface designs to reduce wear.
Leiming Gao   +4 more
doaj   +1 more source

Tailored biomedical materials for wound healing. [PDF]

open access: yesBurns Trauma, 2023
Liu W   +7 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

In vitro corrosion behaviour of phenolic coated nickel–titanium surfaces

open access: yesBiosurface and Biotribology, 2019
The biocompatibility of implantable nickel–titanium biomaterials relies on the quality of their surfaces. In this study, nickel–titanium surfaces are coated with phenolic thin films of tannic acid and pyrogallol with the purpose of studying their ...
Simon Longela, Athanasios Chatzitakis
doaj   +1 more source

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