Results 61 to 70 of about 12,850,910 (306)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Social participation in the health technology incorporation process into Unified Health System

open access: yesRevista de Saúde Pública
OBJECTIVE To describe the current process of social participation in the incorporation of health technologies in Brazil, within the context of the Unified Health System (SUS). METHODS A descriptive study was conducted based on the analysis of official
Aline Silveira Silva   +3 more
doaj   +2 more sources

Office of Technology Assessment List of Publications, September 1985

open access: yes, 1985
A catalog of Office of Technology Assessment (OTA) documents published through ...
Office of Technology Assessment
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Can pyrolysis handle biomedical wastes?: Assessing the potential of various biomedical waste treatment technologies in tackling pandemics

open access: yesScience of The Total Environment
على الصعيد العالمي، لم يتسبب كوفيد-19 في آثار صحية واجتماعية واقتصادية سلبية هائلة فحسب، بل أدى أيضًا إلى قضايا بيئية مثل الزيادة الهائلة في النفايات الطبية الحيوية. تم توليد النفايات الطبية الحيوية (BMW) من مرافق الرعاية الصحية المركزية (المستشفيات والعيادات ومرافق البحوث) والموسعة (معسكرات الحجر الصحي ومعسكرات اختبار COVID -19 والمنازل المعزولة). يتم
Akshay Srivastava   +11 more
openaire   +3 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Clinical investigations for SUS, the Brazilian public health system

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: Scientific and technological development is crucial for advancing the Brazilian health system and for promoting quality of life. The way in which the Brazilian Ministry of Health has supported clinical research to provide autonomy,
Ana Patrícia de Paula   +10 more
doaj   +1 more source

Office of Technology Assessment Semi-Annual Report, July 1994

open access: yes, 1994
This report includes information on technological products released during FY1994, legislation in the 103rd Congress related to the Office of Technology Assessment (OTA), and background information on OTA itself, among other ...
Office of Technology Assessment
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Does the broad dissemination of end-of-life letters for medical devices, including in a national repository, contribute to the implementation of the National Policy on Health Technology Management?

open access: yesVigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia
Introduction: Medical device End-of-Life (EOL) and End-of-Service (EOS) letters, or discontinuation notices, informing the cessation of production and the timeline for technical support, are essential for planning replacement, as well as preventive and ...
Fotini Santos Toscas   +4 more
doaj   +1 more source

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