Results 51 to 60 of about 418,008 (279)

Technological advancements in antibody-based therapeutics for treatment of diseases

Journal of Biomedical Science
Monoclonal antibodies (mAbs) represent a major class of therapeutics with widespread clinical applications in oncology, immunology, hematology, neurology and infectious disease.
Ruei-Min Lu, Hsiao-Ling Chiang, Joyce Pei‑Yi Yuan, Hsiu-Hua Wang, Chi-Yung Chen, Sushree Shankar Panda, Kang-Hao Liang, Hung-Pin Peng, Shih-Han Ko, Hung-Ju Hsu, Monika Kumari, Yi-Jen Su, Yi-Ting Tse, Nai-Lin Chou, Han-Chung Wu   +14 more
doaj   +1 more source

Clinical translation of biomedical materials and the key factors towards product registration

Journal of Orthopaedic Translation, 2014
Biomedical materials have been developed for facilitating tissue regeneration and healing enhancement. Although research on biomedical materials has made great progress in material innovation and preclinical testing, the bottleneck is their translation ...
Yuan Yuan, Dan Lin, Fangping Chen, Changsheng Liu   +3 more
doaj   +1 more source

Identification of Fertile Translations in Medical Comparable Corpora: a Morpho-Compositional Approach [PDF]

, 2012
This paper defines a method for lexicon in the biomedical domain from comparable corpora. The method is based on compositional translation and exploits morpheme-level translation equivalences.
Daille, Béatrice, Delpech, Estelle, Lemaire, Claire, Morin, Emmanuel   +3 more
core   +3 more sources

Use of induced acceleration to quantify the (de)stabilization effect of external and internal forces on postural responses [PDF]

, 2007
Due to the mechanical coupling between the body segments, it is impossible to see with the naked eye the causes of body movements and understand the interaction between movements of different body parts.
Asseldonk, Edwin H.F. van, Carpenter, Mark G., Helm, Frans C.T. van der, Kooij, Herman van der   +3 more
core   +4 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The Meaning Factory at SemEval-2017 Task 9: Producing AMRs with Neural Semantic Parsing [PDF]

, 2017
We evaluate a semantic parser based on a character-based sequence-to-sequence model in the context of the SemEval-2017 shared task on semantic parsing for AMRs.
Bos, Johan, van Noord, Rik
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Current landscape of mRNA technologies and delivery systems for new modality therapeutics

Journal of Biomedical Science
Realizing the immense clinical potential of mRNA-based drugs will require continued development of methods to safely deliver the bioactive agents with high efficiency and without triggering side effects.
Ruei-Min Lu, Hsiang-En Hsu, Ser John Lynon P. Perez, Monika Kumari, Guan-Hong Chen, Ming-Hsiang Hong, Yin-Shiou Lin, Ching-Hang Liu, Shih-Han Ko, Christian Angelo P. Concio, Yi-Jen Su, Yi-Han Chang, Wen-Shan Li, Han-Chung Wu   +13 more
doaj   +1 more source

Cell membrane tensile strain under cyclic compression: A viscoelastic myoblast finite element model

Medicine in Novel Technology and Devices, 2022
Cyclic mechanical stimulation could lead to subsequent biomechanical and biological effects on cells. Viscoelastic cells could deform or show energy dissipation with hysteresis behavior in response to external cyclic compression.
Jingyi Jia, Shurui Chong, Lu Yu, Yifei Yao   +3 more
doaj   +1 more source

Applications of the ACGT Master Ontology on Cancer [PDF]

, 2008
In this paper we present applications of the ACGT Master Ontology (MO) which is a new terminology resource for a transnational network providing data exchange in oncology, emphasizing the integration of both clinical and molecular data.
A. Cali, A. Gómez-Pérez, A.L. Rector, B. Smith, B. Smith, C. Wittekind, J.E. Andrews, J.J. Cimino, K.H. Buetow, L. Martín, M. Tsiknakis, P. Grenon, W. Ceusters, W.A. Schulz   +13 more
core   +3 more sources