Results 91 to 100 of about 72,976 (216)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, Volume 20, Issue 3, Page 850-862, March 2026.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Mètode Science Studies Journal: Annual Review, 2018 La pseudociencia (falsa ciencia) y la ciencia basada en estudios defectuosos y sesgados (mala ciencia) producen conocimiento falso o incierto, sin pruebas o con evidencias de baja calidad.
Gonzalo Casino
doaj +1 more source
Dor crônica: objeto insubordinado Chronic pain: an insubordinate object
História, Ciências, Saúde: Manguinhos, 2008 Discutem-se as lacunas no estudo da dor crônica, bem como as possíveis aberturas e as novas possibilidades no cuidado à saúde, com base no reposicionamento e na interação dos agentes envolvidos.
Mônica Angelim Gomes de Lima, Leny Trad
doaj +1 more source
Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
Avances en el estudio toxicológico de los nanomateriales. Parte I
Mundo NanoDurante los últimos años, el estudio fino de las propiedades de los nanomateriales (NMs) ha transformado la forma de abordar la ciencia de los materiales. Esto ha impactado en todas las áreas del conocimiento, con aplicaciones importantes en biomedicina,
María del Carmen González Castillo +1 more
doaj +1 more source
Do's and Don'ts When Visiting Circularly Polarized Luminescence
Advanced Optical Materials, Volume 14, Issue 11, 20 March 2026.This perspective presents our insights into the principles, challenges, and opportunities of circularly polarized luminescence (CPL). Highlighting key concepts such as the dissymmetry factor (glum) and molecular design strategies, we discuss advances in CPL efficiency, emerging NIR emitters, solid‐state applications, and the growing role of theory and ...
Rafael G. Uceda +9 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2277-2285, March 2026.Abstract Aim To quantify the relative importance of frequency of administration in basal insulin treatment preferences of people living with type 2 diabetes (T2D) in France and Spain, using a discrete choice experiment (DCE). Materials and Methods A targeted literature review and qualitative patient interviews informed an attributes and levels grid ...
Amy M. Jones +9 more
wiley +1 more source
Revista Española de Documentación Científica, 1994 El objetivo de este trabajo es hacer una selección de las publicaciones periódicas básicas que una biblioteca especializada debe contener, en este caso en el área de Biomedicina.
J. Fernández Ferreras +4 more
doaj +1 more source
Nou marcador per detectar el VIH [PDF]
, 2006 Investigadors de l'Institut de Biotecnologia i de Biomedicina de la UAB han aconseguit desenvolupar una nova proteïna, denominada NF795gpC, que actua com un sensor quan entra en contacte amb el sèrum d'un pacient infectat pel VIH (Virus d ...
Ferraz Colomina, Rosa Maria
core +1 more source
Ovarian influence on circadian and infradian modulation of nicotine‐seeking in female mice
Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.Abstract Sex differences in tobacco intake are closely associated with hormonal fluctuations during the menstrual cycle in women. Elevated estrogen levels have been associated with increased stress, which may lead to a higher likelihood of seeking psychoactive substances.
Zenaida Rosas‐Ovando +9 more
wiley +1 more source