Results 101 to 110 of about 406,090 (330)

Biomedical Trends in Stimuli-Responsive Hydrogels with Emphasis on Chitosan-Based Formulations

open access: yesGels
Biomedicine is constantly evolving to ensure a significant and positive impact on healthcare, which has resulted in innovative and distinct requisites such as hydrogels.
Weronika Kruczkowska   +9 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Appraisal of Comparative Therapeutic Potential of Undoped and Nitrogen-Doped Titanium Dioxide Nanoparticles

open access: yesMolecules, 2019
Nitrogen-doped and undoped titanium dioxide nanoparticles were successfully fabricated by simple chemical method and characterized using x-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive x-ray (EDX), and transmission electron
Muhammad Arslan Ahmad   +5 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Optical Nanoparticles for Biomedicine

open access: yesBiomedicines, 2022
A great variety of particles of different compositions and shapes with typical sizes in the range 1–200 nm have been developed during the first years of this century [...]
openaire   +3 more sources

Biomedical Application Prospects of Gadolinium Oxide Nanoparticles for Regenerative Medicine

open access: yesPharmaceutics
Background/Objectives: The aim was to study the possibilities of biomedical application of gadolinium oxide nanoparticles (Gd2O3 NPs) synthesized under industrial conditions, and evaluate their physicochemical properties, redox activity, biological ...
Ekaterina V. Silina   +9 more
doaj   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

On the use of Networks in Biomedicine

open access: yesProcedia Computer Science, 2017
Abstract The concept of “neural network” emerges by electronic models inspired to the neural structure of human brain. Neural networks aim to solve problems currently out of computer's calculation capacity, trying to mimic the role of human brain. Recently, the number of biological based applications using neural networks is growing up.
Eugenio Vocaturo, Pierangelo Veltri
openaire   +3 more sources

Life Sciences, Medicine and Biomedicine – supporting open access publishing

open access: yesLife Sciences, Medicine and Biomedicine
As an open access journal, Life Sciences, Medicine and Biomedicine (LSMB) has made remarkable progress. LSMB is currently indexed by MyJurnal, the Directory of Open Access Journals (DOAJ), the Malaysian Citation Index (MyCite) and Scilit. Data shows that
Editorial
doaj   +1 more source

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