Results 81 to 90 of about 187,595 (255)

Thank you to reviewers of negative results in 2015

open access: yesAll Results Journals: Biol, 2015
The mission of The All Results Journals:Biol is the communication of excellent research work obtaining negative results from all fields of biology and biomedicine. Clearly, a scientific journal’s greatest responsibility toward the scientific community is
David Alcantara
doaj  

Biomedical Trends in Stimuli-Responsive Hydrogels with Emphasis on Chitosan-Based Formulations

open access: yesGels
Biomedicine is constantly evolving to ensure a significant and positive impact on healthcare, which has resulted in innovative and distinct requisites such as hydrogels.
Weronika Kruczkowska   +9 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Front Matter Vol 3 No 1

open access: yesCurrent Biomedicine
Front Matter Vol 3 No ...
Current Biomedicine
doaj  

Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine

open access: yesNanomaterials
Electrospinning has emerged as a versatile and cost-effective technique for fabricating nanofibers with a high surface area, tunable morphology, and exceptional mechanical properties, demonstrating significant potential for applications in biomedicine ...
Jingwen Liu   +5 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

The HEPS synchrotron unleashes new medical frontiers

open access: yesJournal of Synchrotron Radiation
The High Energy Photon Source (HEPS) in Beijing achieved a beam energy of 6 GeV. This milestone enables groundbreaking advances in health sciences and various research fields, promising new insights into biological and quantum processes.
Jishizhan Chen, Chong Chen
doaj   +1 more source

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