Results 101 to 110 of about 233,577 (305)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

WS47: Drugs Affecting 5-HT Systems (20-Nov-2012)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “Drugs Affecting 5-HT Systems” held by the History of Modern Biomedicine Research Group, 20-Nov-2012.

core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

WS55: A History of Bovine TB c.1965–c.2000 (13-May-2014)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “A History of Bovine TB c.1965–c.2000" held by the History of Modern Biomedicine Research Group, 13-May-2014. Participants: Dr Angela Cassidy, Mr Michael Clark, Dr Gareth Davies, Professor Wyn Grant (Chair)

core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

WS45: Palliative Medicine in the UK c.1970-2010 (28-Feb-2012)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “Palliative Medicine in the UK c.1970-2010” held by the History of Modern Biomedicine Research Group, 28-Feb-2012.

core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

WS41: History of the National Survey of Sexual Attitudes and Lifestyles (14-Dec-2009)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “History of the National Survey of Sexual Attitudes and Lifestyles” held by the History of Modern Biomedicine Research Group,14-Dec-2009.

core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

WS60: The Recent History of Tumour Necrosis Factor (TNF)(14-Jul-2015)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “The Recent History of Tumour Necrosis Factor (TNF)" held by the History of Modern Biomedicine Research Group, 14-Jul-2015.

core  

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