Results 71 to 80 of about 475,736 (375)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A note on comparison of scientific impact expressed by the number of citations in different fields of science [PDF]
, 2004 Citation distributions for 1992, 1994, 1996, 1997, 1999, and 2001, which were published in the 2004 report of the National Science Foundation, USA, are analyzed.
Podlubny, Igor
core +3 more sources
How Machine Learning Will Transform Biomedicine.
Cell, 2020 This Perspective explores the application of machine learning toward improved diagnosis and treatment. We outline a vision for how machine learning can transform three broad areas of biomedicine: clinical diagnostics, precision treatments, and health ...
Jeremy Goecks +3 more
semanticscholar +1 more source
Topological data analysis in biomedicine: A review
Journal of Biomedical Informatics, 2022 Significant technological advances made in recent years have shepherded a dramatic increase in utilization of digital technologies for biomedicine- everything from the widespread use of electronic health records to improved medical imaging capabilities ...
Yara Skaf, Reinhard C. Laubenbacher
semanticscholar +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Sensors, 2022 In the modern technological era, Anti-cancer peptides (ACPs) have been considered a promising cancer treatment. It’s critical to find new ACPs to ensure a better knowledge of their functioning processes and vaccine development. Thus, timely and efficient
Majed Alsanea +6 more
doaj +1 more source
It's money that matters: the financial context of ethical decision-making in modern biomedicine [PDF]
, 2006 While the importance of patient autonomy is widely acknowledged and discussed in the bioethics literature, clinicians' autonomy, their ability to make the best choices about patients' care free from outside interference, is far less debated.
Birch +39 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Magnetic Nanoparticle Composites: Synergistic Effects and Applications
Advanced Science, 2021 Composite materials are made from two or more constituent materials with distinct physical or chemical properties that, when combined, produce a material with characteristics which are at least to some degree different from its individual components ...
Stefanos Mourdikoudis +2 more
doaj +1 more source
Microfocal X-Ray Computed Tomography Post-Processing Operations for Optimizing Reconstruction Volumes of Stented Arteries During 3D Computational Fluid Dynamics Modeling [PDF]
, 2005 Restenosis caused by neointimal hyperplasia (NH) remains an important clinical problem after stent implantation. Restenosis varies with stent geometry, and idealized computational fluid dynamics (CFD) models have indicated that geometric properties of ...
Haworth, Steven Thomas +7 more
core +1 more source