Results 71 to 80 of about 253,550 (273)
Biomanufacturing: from biomedicine to biomedicine [PDF]
Bio-Design and Manufacturing, 2021 openaire +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Integrative Medicine: In With the New
Journal of Patient-Centered Research and Reviews, 2015 Integrative medicine is not "alternative," which implies the substitution of conventional medicine with often unproven natural treatments. Rather, integrative medicine is defined as the combination of conventional biomedicine with nontraditional and ...
Tiffany A. Mullen
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Continuous Distant Measurement of the User’s Heart Rate in Human-Computer Interaction Applications
Sensors, 2019 In real world scenarios, the task of estimating heart rate (HR) using video plethysmography (VPG) methods is difficult because many factors could contaminate the pulse signal (i.e., a subjects’ movement, illumination changes). This article presents
Jaromir Przybyło
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Thank you to reviewers of negative results in 2015
All Results Journals: Biol, 2015 The mission of The All Results Journals:Biol is the communication of excellent research work obtaining negative results from all fields of biology and biomedicine. Clearly, a scientific journal’s greatest responsibility toward the scientific community is
David Alcantara
doaj
Biomedical Trends in Stimuli-Responsive Hydrogels with Emphasis on Chitosan-Based Formulations
GelsBiomedicine is constantly evolving to ensure a significant and positive impact on healthcare, which has resulted in innovative and distinct requisites such as hydrogels.
Weronika Kruczkowska +9 more
doaj +1 more source