Results 51 to 60 of about 253,550 (273)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Role of Phages in Past Molecular Biology and Potentially in Future Biomedicine
EncyclopediaViruses that infect bacteria (bacteriophages or phages) have a history of use in both biomedicine and basic molecular biology. Here, I briefly outline the pre-1940 use of phages in biomedicine and then more comprehensively outline the subsequent use of ...
Philip Serwer
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Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
WS53: The Development of Brain Banks in the UK c.1970–c.2010 (12-Nov-2013)
, 2017 Selection of photos taken at the Witness Seminar “The Development of Brain Banks in the UK c.1970–c.2010” held by the History of Modern Biomedicine Research Group, 12-Nov-2013.
core +3 more sources
Nanotechnology advances for biomedical applications
Frontiers in NanotechnologyNanotechnology has recently emerged as a revolutionary force in the field of biomedical science, offering innovative solutions to complex challenges in diagnostics, drug delivery, tissue engineering, and disease therapeutics.
Lekshmi Gangadhar, Saranyadevi Subburaj
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Frontiers in PharmacologyBackgroundDespite therapeutic interventions, tuberculosis (TB) remains a persistent challenge. Combination therapy integrating Traditional Chinese Medicine (TCM) with conventional anti-TB medications demonstrates therapeutic benefits, necessitating a ...
Jiankang Jiang +12 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Informed consent to the receipt and use of human cellular material: juristic and ethical regulation
Российский кардиологический журнал, 2018 Further progress in medicine is closely related to the clinical introduction of regenerative technologies, including cell therapy. Presented article covers the ethical and legal status of obtaining an informed consent from donors of cell material.
D. V. Stambolsky +7 more
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