Results 51 to 60 of about 187,595 (255)
Hydrophobic Interaction: A Promising Driving Force for the Biomedical Applications of Nucleic Acids
Advanced Science, 2020 The comprehensive understanding and proper use of supramolecular interactions have become critical for the development of functional materials, and so is the biomedical application of nucleic acids (NAs).
Fan Xiao +3 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Role of Phages in Past Molecular Biology and Potentially in Future Biomedicine
EncyclopediaViruses that infect bacteria (bacteriophages or phages) have a history of use in both biomedicine and basic molecular biology. Here, I briefly outline the pre-1940 use of phages in biomedicine and then more comprehensively outline the subsequent use of ...
Philip Serwer
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Biocatalysis by Transglutaminases: A Review of Biotechnological Applications
Micromachines, 2018 The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopeptide bonds (crosslinks) between peptide-bound glutamine and lysine residues, but also the transamidation of primary amines to glutamine residues, which ...
Maria Pia Savoca +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Development of the portable cold plasma source for biomedical applications
St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2021 A cold plasma source (CPS) developed by us has been put forward. The operating principle of the device is based on the use of a pulsed positive corona discharge at atmospheric pressure. The CPS exhibits compactness and autonomy.
Feklistov Efrem
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Nanotechnology advances for biomedical applications
Frontiers in NanotechnologyNanotechnology has recently emerged as a revolutionary force in the field of biomedical science, offering innovative solutions to complex challenges in diagnostics, drug delivery, tissue engineering, and disease therapeutics.
Lekshmi Gangadhar, Saranyadevi Subburaj
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Frontiers in PharmacologyBackgroundDespite therapeutic interventions, tuberculosis (TB) remains a persistent challenge. Combination therapy integrating Traditional Chinese Medicine (TCM) with conventional anti-TB medications demonstrates therapeutic benefits, necessitating a ...
Jiankang Jiang +12 more
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