Results 111 to 120 of about 466,709 (358)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Learning and Shaping Expert Knowledges: The Case of Precision Medicine
Sociologica, 2019 The aim of this article – drawing on broad ethnographic research within two major Italian organisations operating in cancer care and research – is to enlarge practice-based studies, and in particular the practice-based approach to learning.
Stefano Crabu
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Economic Evaluation of Regional Innovative Projects in the Sphere of Biomedicine [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2016 The article deals with the cost-effectiveness analysis of innovative projects in the sphere of biomedicine. The analysis of these projects makes it possible to estimate the economic benefits of the projects and will contribute to the commercialization of
Oleg N. Shishatskiy
doaj
Chitosan-Based (Nano)Materials for Novel Biomedical Applications
Molecules, 2019 Chitosan-based nanomaterials have attracted significant attention in the biomedical field because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature.
Gregor Kravanja +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Responsive nanomaterials in biomedicine, patent path and prospect analysis
Frontiers in Bioengineering and BiotechnologyIn recent years, responsive nanomaterials have demonstrated tremendous potential in biomedical applications due to their unique advantages in precise drug delivery and controlled release.
Xinrui Liu, Hongmei Yuan
doaj +1 more source
The Medical Cosmology of Halakha: The Expert, the Physician, and the Sick Person on Shabbat in the Shulchan Aruch [PDF]
, 2018 One of the best-known principles of halakha is that Shabbat is violated to save a life. Who does this saving and how do we know that a life is in danger? What categories of illness violate Shabbat and who decides?
Berger, Zackary
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The odd couple: using biomedical and intersectional approaches to address health inequities
Global Health Action, 2017 Background: Better understanding and addressing health inequities is a growing global priority. Objective: In this paper, we contribute to the literature examining complex relationships between biological and social dimensions in the field of health ...
Olena Hankivsky +6 more
doaj +1 more source