Results 121 to 130 of about 406,090 (330)
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
, 2013 The focus of my research is on contemporary biomedical construction of pain as an object, i.e. the different ways in which pain has been conceptualized and approached as a specific site of investigation in biomedicine. A significant shift in the scientific conception of pain occured in the second half of XXth century.
openaire +2 more sources
Integrative Medicine: In With the New
Journal of Patient-Centered Research and Reviews, 2015 Integrative medicine is not "alternative," which implies the substitution of conventional medicine with often unproven natural treatments. Rather, integrative medicine is defined as the combination of conventional biomedicine with nontraditional and ...
Tiffany A. Mullen
doaj +1 more source
Free-electron lasers and their application to biomedicine [PDF]
, 1987 B.G. Danly, Richard J. Temkin, G. Bekefi
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiation therapy induces cancer cell death and immune cell infiltration, mainly monocytes, macrophages, and dendritic cells. Elevated serum cytokine levels and disruption of the blood–brain barrier promote leptomeningeal dissemination. Cotreatment with dexamethasone reduces cytokine levels, preserves barrier integrity, and limits metastatic spread ...
Francis Y. He, Adrienne Boire
wiley +1 more source
Drum and stethoscope: integrating ethnomedicine and biomedicine in Bolivia [PDF]
, 1993 Nancy M. Flowers
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Editorial: Methods and applications in clinical and translational physiology
Frontiers in Physiology, 2023 Gaetano Santulli +5 more
doaj +1 more source