Results 11 to 20 of about 69,209 (254)

Calorie restriction has no effect on bone marrow tumour burden in a Vk*MYC transplant model of multiple myeloma

Scientific Reports, 2022
Multiple myeloma (MM) is an incurable haematological malignancy, caused by the uncontrolled proliferation of plasma cells within the bone marrow (BM). Obesity is a known risk factor for MM, however, few studies have investigated the potential of dietary ...
Alanah L. Bradey, Stephen Fitter, Jvaughn Duggan, Vicki Wilczek, Connor M. D. Williams, Emma AJ. Cheney, Jacqueline E. Noll, Pawanrat Tangseefa, Vasilios Panagopoulos, Andrew C. W. Zannettino   +9 more
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H3K27ac mediated SS18/BAFs relocation regulates JUN induced pluripotent-somatic transition

Cell & Bioscience, 2022
Background The exit from pluripotency or pluripotent-somatic transition (PST) landmarks an event of early mammalian embryonic development, representing a model for cell fate transition.
Runxia Lin, Ziwei Zhai, Junqi Kuang, Chuman Wu, Yuxiang Yao, Ruona Shi, Jiangping He, Shuyang Xu, Pengli Li, Yixin Fan, Wei Li, Zichao Wu, Xiaoxi Li, Jin Ming, Jing Guo, Bo Wang, Dongwei Li, Shangtao Cao, Xiaofei Zhang, Yi Li, Duanqing Pei, Jing Liu   +21 more
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Arsenic trioxide-induced apoptosis contributes to suppression of viral reservoir in SIV-infected rhesus macaques

Microbiology Spectrum, 2023
Latent viral reservoir is recognized as the major obstacle to achieving a functional cure for HIV infection. We previously reported that arsenic trioxide (As2O3) combined with antiretroviral therapy (ART) can reactivate the viral reservoir and delay ...
Yizi He, Chunxiu Wu, Zijian Liu, Yudi Zhang, Fengling Feng, Zihan Lin, Congcong Wang, Qing Yang, Ziyu Wen, Yichu Liu, Fan Zhang, Yanqin Lin, Hao Zhang, Linbing Qu, Linghua Li, Weiping Cai, Caijun Sun, Ling Chen, Pingchao Li   +18 more
doaj   +1 more source

Prevalence and Current Practices of Self-Medication among Students of the Biomedicine Degree at the Health Sciences School

International Journal for Innovation Education and Research, 2020
Self-medication is often seen as a solution for the immediate relief of symptoms, however, bringing serious consequences to consumer's health and serious public health problems in Brazil and the world. Still, regarding self-medication, the conduct of University students in the health area is observed, since the habit in this group is high.
Mariane Gabriela Terezani, Elís Claudia Ribeiro Cantarella, Luciana Estevam Simonato, Wagner Rafael da Silva, José Martins Pinto Neto, André Wilian Lozano, Luis Lênin Vicente Pereira, Rogério Rodrigo Ramos   +7 more
openaire   +2 more sources

DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells

OncoImmunology, 2019
Chimeric antigen receptor (CAR) T cell immunotherapies have shown remarkable efficacy in treating multiple types of hematological malignancies but are not sufficiently effective at treating solid tumors. NKG2D is a strong activating receptor for NK cells
Ruocong Zhao, Lin Cheng, Zhiwu Jiang, Xinru Wei, Baiheng Li, Qiting Wu, Suna Wang, Simiao Lin, Youguo Long, Xuchao Zhang, Yilong Wu, Xin Du, Duanqing Pei, Pentao Liu, Yangqiu Li, Shuzhong Cui, Yao Yao, Peng Li   +17 more
doaj   +1 more source

A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine

Emerging Microbes and Infections, 2023
African swine fever (ASF) is an acute and highly contagious lethal infectious disease in swine that severely threatens the global pig industry. At present, a safe and efficacious vaccine is urgently required to prevent and control the disease.
Wenming Liu, Hengchun Li, Bo Liu, Tianxing Lv, Chenchen Yang, Si Chen, Liqiang Feng, Liangxue Lai, Ziyuan Duan, Xinwen Chen, Pingchao Li, Suhua Guan, Ling Chen   +12 more
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Biopolitics, biotechnologies, biomedicine, and biolaw as forms of bioregulation [PDF]

SHS Web of Conferences, 2021
Modern science, education, and medicine are increasingly becoming the primary agents of biopolitics. Biomedicine is emerging, and before our eyes, it is becoming a part of the social sphere and, in the long term, a part of the new economic order and one ...
Mokhov Aleksandr Anatolyevich, Levushkin Anatolii Nikolaevich, Yavorskiy Aleksander Nikolaevich   +2 more
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Modeling Congenital Hyperinsulinism with ABCC8-Deficient Human Embryonic Stem Cells Generated by CRISPR/Cas9

Scientific Reports, 2017
Congenital hyperinsulinism (CHI) is a rare genetic disorder characterized by excess insulin secretion, which results in hypoglycemia. Mutation of sulfonylurea receptor 1 (SUR1), encoded by the ABCC8 gene, is the main cause of CHI.
Dongsheng Guo, Haikun Liu, Aynisahan Ruzi, Ge Gao, Abbas Nasir, Yanli Liu, Fan Yang, Feima Wu, Guosheng Xu, Yin-xiong Li   +9 more
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MYB bi-allelic targeting abrogates primitive clonogenic progenitors while the emergence of primitive blood cells is not affected

Haematologica, 2020
MYB is a key regulator of definitive hematopoiesis and it is dispensable for the development of primitive hematopoietic cells in vertebrates. To delineate definitive versus primitive hematopoiesis during differentiation of human embryonic stem cells, we ...
Zahir Shah, Elena S. Filonenko, Vasily Ramensky, Chenyu Fan, Cuihua Wang, Hanif Ullah, Baoyun Zhang, Pavel Volchkov, Igor M. Samokhvalov   +8 more
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Artificial intelligence (AI) meets biomaterials and biomedicine

Smart Materials in Medicine
With the rapid progress of information technology and life sciences, artificial intelligence (AI) technology has substantially changed the way in many areas of biomaterials and biomedicine, including biomaterials and formulation design, drug development,
Shuyan Han, Jun Wu
doaj   +1 more source