Results 81 to 90 of about 7,346 (256)

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley   +3 more
wiley   +1 more source

User privacy prevention model using supervised federated learning‐based block chain approach for internet of Medical Things

open access: yesCAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract This research focuses on addressing the privacy issues in healthcare advancement monitoring with the rapid establishment of the decentralised communication system in the Internet of Medical Things (IoMT). An integrated blockchain homomorphic encryption standard with an in‐build supervised learning‐based smart contract is designed to improvise ...
Chandramohan Dhasarathan   +7 more
wiley   +1 more source

Harnessing Generative AI for Sustainable Supply Chains: Lean, Circular and Green Perspectives

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Generative artificial intelligence is playing a significant role in the transformation of digital ecosystems by reinventing the processes of content generation, process automation, product innovation and customer experience. At the same time that these technologies are becoming more integrated into routine operations, the focus has shifted to ...
Ashutosh Singh   +3 more
wiley   +1 more source

The agrocenotic resistance of different winter wheat varieties to weed infestation under the conditions of the Steppe zone of Ukraine

open access: yesКарантин і захист рослин
Goal. To identify winter wheat varieties of different maturity groups that exhibit agrocenotic resistance to weeds, based on modern resistant cultivars. Methods.
V. Matyukha, O. Tsyliuryk, S. Semenov
doaj   +1 more source

Biometric Analysis – A Reliable Indicator for Diagnosing Taurodontism using Panoramic Radiographs

open access: yesJOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2013
Taurodontism is a clinical entity with a morpho-anatomical change in the shape of the tooth, which was thought to be absent in modern man. Taurodontism is mostly observed as an isolated trait or a component of a syndrome. Various techniques have been devised to diagnose taurodontism.The aim of this study was to analyze whether a biometric analysis was ...
Veda Hegde   +2 more
openaire   +3 more sources

Innovation and Growth Investment Through Capital Expenditure as a Channel and Boundary Condition Between Financial Performance and Corporate Reputation

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the role of capital expenditure in the relationship between financial performance and corporate reputation. Using moderation and mediation analyses based on multiple regressions with bootstrapping, we examined data from 121 airlines from 46 countries during 2007–2023.
Larissa M. Batrancea   +2 more
wiley   +1 more source

EVALUATION OF THE EFFECTIVENESS OF THE BIOLOGICAL AND CHEMICAL POTATO PLANT PROTECTION SYSTEM AGAINST THE BACKGROUND OF VARIOUS WATER REGIMES DURING SPRINKLING IRRIGATION IN THE LOWER VOLGA REGION

open access: yesМелиорация и гидротехника
Purpose: to develop optimal combinations of parameters of the soil water regime and elements of the plant protection system in conditions of region hydrothermal tension on the basis on a comprehensive assessment of the biological potential of potato ...
Alexey A. Novikov, Konstantin A. Rodin
doaj   +1 more source

Orchestrating Green Transformation: How AI Adoption Enables Corporate Carbon Neutrality

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT As carbon neutrality has become a central goal of global climate governance, how firms achieve low‐carbon transformation has emerged as a critical research issue. However, prior studies have primarily focused on macro‐ or industry‐level analyses, offering limited and fragmented insights into how digital technologies—particularly AI—affect firm‐
Xiaonan Dong, Sungjin Son
wiley   +1 more source

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