Inspired by metal‐free carbonic anhydrases (CAs) that achieve efficient catalysis without metal cofactors, we herein report a sequence‐defined supramolecular peptoid platform that mimics metal‐free CAs and exhibits hydrolytic activity via a supramolecular assembly‐mediated proton‐transfer mechanism.
Progyateg Chakma +8 more
wiley +1 more source
Marine Anoxia and Ocean Acidification During the End‐Permian Extinction
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Ying Cui +4 more
wiley +1 more source
Objective This study aimed to compare the differences in pyroptosis and polarization of macrophages induced by different sizes of calcium oxalate monohydrate (COM) crystals and discuss the mechanism of kidney stone formation.
Xin-Yi Tong +3 more
doaj +1 more source
Size-dependent pyroptosis induction by calcium oxalate monohydrate crystals in HK-2 cells
Summary: This article explored the differences in pyroptosis mediated by calcium oxalate monohydrate (COM) crystals with sizes of 100 nm, 1 μm, 3 μm, 5 μm, and 10 μm and were used to induce pyroptosis of HK-2 cells. The proportion of pyroptosis cells was
Xue-Wu Chen +3 more
doaj +1 more source
Kinetic theory and numerical simulation of biomineralization
The biomineralization technology that becomes an emerging research topic has attracted wide attentions in recent years. However, it is hard to quantify the reaction process of biomineralization on temporal and spatial scales due to its complicated ...
ZHAO Chang 1, HE Xiang 1, HU Ran 2, LIU Han-long 1, XIE Qiang 1, WANG Yu-ze 3, WU Huan-ran 1, XIAO Yang 1
doaj +1 more source
The shell of the pearl oyster Pinctada margaritifera is made up of two layers: an outer layer of calcite prisms and an inner layer of aragonite tablets. Recent studies have shown that the calcite layer develops in a series of steps. We found that the end
Cedrik Lo +5 more
core +1 more source
Flax Composites With Improved Interfacial Strength Through Microbially Induced Mineral Precipitation
A bio‐inspired biomineralization strategy introduces an additional hierarchy to flax fiber composites. By controlling microbe‐mediated mineral particle deposition through tuned salt concentrations, stress transfer within the natural fiber composite is enhanced.
Deniz Sayinbas +5 more
wiley +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Pathological ECM remodelling and biomineralization in human aortic valve and bioprosthesis tissue were investigated by Fourier transformed infrared (FT-IR) spectroscopic imaging and multivariate data analysis.
Claudia Dittfeld +6 more
core +1 more source
Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo +15 more
wiley +1 more source

