Results 71 to 80 of about 58,605 (360)

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Comparison of Endoplasmic Reticulum Stress and Pyroptosis Induced by Pathogenic Calcium Oxalate Monohydrate and Physiologic Calcium Oxalate Dihydrate Crystals in HK-2 Cells: Insights into Kidney Stone Formation

open access: yesCells
Endoplasmic reticulum stress (ERS) can activate pyroptosis through CHOP and TXNIP; however, the correlation between this process and the formation of kidney stones has not been reported.
Wei-Jian Nong   +2 more
doaj   +1 more source

Magnetosome vesicles are present before magnetite formation, and MamA is required for their activation [PDF]

open access: yes, 2004
Bacterial magnetosomes are intracellular compartments that house highly ordered magnetite crystals. By using Magnetospirillum sp. AMB-1 as a model system, we show that magnetosome vesicles exist in the absence of magnetite, biomineralization of magnetite
Beveridge, Terrance J.   +3 more
core  

RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins [PDF]

open access: yes, 2016
The sea urchin larval skeleton offers a simple model for formation of developmental patterns. The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown patterning cues expressed by the ectoderm.
Bardot, Evan   +26 more
core   +1 more source

Anisotropic Shear Properties of Organic Interfaces in Bio‐composite Materials

open access: yesAdvanced Functional Materials, EarlyView.
A novel cantilever design enables direct probing of shear properties at single organic interfaces within biocomposite prismatic ultrastructures. By decoupling lateral and torsional shear responses, the method reveals isotropic behavior in Atrina vexillum and pronounced anisotropy in Unio pictorum.
Kian Tadayon   +2 more
wiley   +1 more source

Different Degrees of Sulfated Laminaria Polysaccharides Recovered Damaged HK-2 Cells and Inhibited Adhesion of Nano-COM and Nano-COD Crystals

open access: yesBioinorganic Chemistry and Applications
Purpose. The crystal adhesion caused by the damage of renal tubular epithelial cells (HK-2) is the key to the formation of kidney stones. However, no effective preventive drug has been found.
Qiu-Shi Xu   +5 more
doaj   +1 more source

Composition and Morphology of Nanocrystals in Urines of Lithogenic Patients and Healthy Persons

open access: yesBioinorganic Chemistry and Applications, 2009
The composition and morphology of nanocrystals in urines of healthy persons and lithogenic patients were comparatively investigated by means of X-ray diffraction (XRD) and transmission electron microscopy (TEM).
Bao-Song Gui   +4 more
doaj   +1 more source

A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]

open access: yes, 2015
Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin   +5 more
core   +2 more sources

Multiple Twinning in Nacre and Aragonite

open access: yesAdvanced Functional Materials, EarlyView.
Electron backscatter diffraction map of a cluster of geologic aragonite, exhibiting single, double, and triple twins. The whole cluster is approximately 2 cm wide. Colors indicate crystal orientations, so that pixels where the a‐, b‐, and c‐axis is perpendicular to the image plane are green, red, and blue, respectively.
Connor A. Schmidt   +7 more
wiley   +1 more source

Coralline algae in a naturally acidified ecosystem persist by maintaining control of skeletal mineralogy and size [PDF]

open access: yes, 2016
To understand the effects of ocean acidification (OA) on marine calcifiers, the trade-offs among different sublethal responses within individual species and the emergent effects of these trade-offs must be determined in an ecosystem setting.
Gambi, M.C.   +4 more
core   +1 more source

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