Results 171 to 180 of about 30,350 (261)

Rheological Characterization of a Low‐Concentration Water‐Based Collagen Dispersion Under Extensional, Shear, and Oscillatory Deformation

Polymer Engineering &Science, EarlyView.
Combined capillary and oscillatory rheology provided complementary insights into the linear, nonlinear, and extensional flow behavior of a 3 wt% collagen dispersion, improving the understanding of its processing‐relevant rheological characteristics. ABSTRACT This study presents an investigation of the extensional, shear, and oscillatory rheological ...
Fadi Alzarzouri, Xiaohe Xu, Manfred Wilhelm, Jan Skočilas   +3 more
wiley   +1 more source

Correction: Electrochemical detection of chlorogenic acid in green coffee beans by a carbon paste electrode modified with MWCNTs and Cr-MOF. [PDF]

RSC Adv
Khayatkashani M, Almansarawi SA, Honarmand E, Sadeghi FS, Ehsani A, Jasim LS, Salavati-Niasari M.   +6 more
europepmc   +1 more source

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Research and development financing models for new biopharmaceuticals in the United States. [PDF]

Health Aff Sch
Kang SY, Lee B, Gupta R, Ballreich J, Anderson G.   +4 more
europepmc   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Advanced oral drug delivery systems: Current challenges and emerging technologies. [PDF]

Acta Pharm Sin B
Onoue S, Yamada K, Sato H.
europepmc   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Biopharmaceutic

Journal of Pharmacy and Pharmacology, 2006
openaire   +1 more source

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina, Stefan Franzén, Maria C. Kjellsson   +2 more
wiley   +1 more source

Human and financial consequences of herding in oncology drug development: clinical trials of TIGIT inhibitors. [PDF]

BMJ Oncol
Zhang ES, Osipenko L, Hickman JA.
europepmc   +1 more source