Results 181 to 190 of about 47,170 (292)

Accessing Both Electrochemical SEIRA and SERS With Highly Sensitive Metamaterials for Enhanced Molecular Identification

Small, EarlyView.
Surface‐enhanced infrared absorption (SEIRA) and Raman scattering (SERS) are complementary, highly sensitive molecular detection methods. A reusable metamaterial substrate capable of combined SEIRA and SERS is used here for real‐time sensing, tracking interfacial dynamics in an electrochemical reaction and detecting symmetry‐breaking behavior at the ...
Nicolas Spiesshofer, Tabitha Jones, Sarah May Sibug‐Torres, Zoltan Sztranyovszky, Caleb Todd, Shijie Zhu, Yeeun Roh, Rakesh Arul, Alexander Squires, Ivana Qianqi Lin, Angela Demetriadou, David O. Scanlon, Viv Lindo, Jeremy J. Baumberg   +13 more
wiley   +1 more source

A <i>Ganoderma lucidum</i> Polysaccharide-Modified Nanoadjuvant Elicits Potent Cellular Immunity for Hepatitis B Vaccine. [PDF]

Vaccines (Basel)
Zhai Z, You J, Liu X.
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Safety, pharmacokinetics, pharmacodynamics and antitumor activity of legubicin in patients with advanced solid tumors, including lung cancer: a phase 1 dose-escalation and expansion trial. [PDF]

BMC Cancer
Lin F, Xue J, Li Q, Tang W, Zhao W, Xue L, Zhou J, Liu Y, Jin W, Sun H, Liu C, Guo Y, Li J.   +12 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Correction: USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression. [PDF]

Cell Death Dis
Haowei Z, Li X, Liao W, Qin X, Jiang Y, Yang H, Zeng H, Li Y, Xie W, Zhang Y, Xu N.   +10 more
europepmc   +1 more source

Effects of Obstructive Sleep Apnea on Personality and Temperament: A Cohort and Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is associated with neurocognitive impairment, but its causal relationship with personality traits remains poorly understood. This study investigates the association and causality between OSA and personality using both cohort and genetic data.
Jian‐Hong Liao, Yun‐Han Shi, Xin‐Peng Xu, Yan‐Ru Li, De‐Min Han   +4 more
wiley   +1 more source

Publisher Correction: Mammalian synthetic gene circuits for biopharmaceutical development & manufacture. [PDF]

NPJ Syst Biol Appl
Lim SLY, Gialamoidou S, Kaur R, Jimenez Del Val I.   +3 more
europepmc   +1 more source

Skin Abnormalities at Checkpoint Inhibitor Therapy Initiation Are Associated With Skin Rash Development in Oncology Patients

Allergy, EarlyView.
Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.
Taras Lyubchenko, Evgeny Berdyshev, Ryan M. Weight, Olivia Xiao, Neil J. Shah, Alina Markova, Mario E. Lacouture, Jeffrey A. Kern, Elena Goleva, Donald Y. M. Leung   +9 more
wiley   +1 more source