Results 181 to 190 of about 30,350 (261)

Revisiting industry effects: The assignment of firms to industries

Strategic Management Journal, EarlyView.
Abstract Research Summary Strategy research examines the drivers of firm performance. Variance decomposition studies have analyzed industry's impact, with little attention paid to the industry to which a firm is assigned. This study investigates how industry assignment affects the findings about industry's impact.
Alireza Eshraghi, Bart S. Vanneste
wiley   +1 more source

Edible mushrooms as emerging biofactories for natural therapeutics and oral biopharmaceutical delivery. [PDF]

Front Fungal Biol
Wang K, Wang A, Meade B.
europepmc   +1 more source

Thermosensitive Nanostructured Coacervates Developed by Mixing ABA‐ and AB‐Block Copolymers and Their Unique Sustained Release of Nano‐Micelles in a Regulated Manner

Small, EarlyView.
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira, Hiroshi Kamizawa, Yujiro Hamada, Wataru Fushimoto, Hiroshi Y. Yoshikawa, Yuji Higaki, Atsushi Takahara, Takeshi Mori, Yoshiki Katayama, Akihiro Kishimura   +9 more
wiley   +1 more source

Biopharmaceutical analysis - current analytical challenges, limitations, and perspectives. [PDF]

Anal Bioanal Chem
Cunha DR, Quinaz MB, Segundo MA.
europepmc   +1 more source

A Label‐Free Ultraviolet Photoacoustic Microscopy Enables Nuclear Imaging and Toxicity Assessment in an Intact Brain Organoid

Small, EarlyView.
Ultraviolet photoacoustic microscopy enables label‐free visualization of nuclear morphology in intact human brain organoids. By exploiting endogenous nucleic acid absorption at 266 nm, this approach resolves individual nuclei without staining or sectioning.
Hyunjun Kye, Won Jong Yu, Lihong V. Wang, Jeesu Kim, Jong‐Chan Park, Byullee Park   +5 more
wiley   +1 more source

A Call To Action: Developing an Agile Global Regulatory Affairs Workforce for the Future. [PDF]

Ther Innov Regul Sci
AlJuburi L, Mahoney N, Reilly E, Bertha A, Isom DC, Bisordi F, Beakes-Read V, Garvin M, Boyce D, Carl K, Curtis SP, Dudinak J, Garner CO, Latif N, Luik S, Rohrer M, Rupalla K, Taisey M, Votzmeyer R, Wegner M, Williams K.   +20 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

CRISPR-Cas9-mediated therapeutics: Current clinical trials and therapy approval landscape to treat human diseases. [PDF]

Mol Ther Nucleic Acids
Chakraborty C, Bhattacharya M, Das A, Agoramoorthy G, Lee SS.   +4 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Models attempting to quantify the relationship between drug development and financial return are missing a key element: the effect on post-approval research. [PDF]

Health Aff Sch
Crippen D, Axelsen K.
europepmc   +1 more source