Results 191 to 200 of about 47,170 (292)

Regulatory economics of global biopharmaceutical manufacturing

core  

Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures

Allergy, EarlyView.
This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally, Takeshi Yoshida, Shan Gao, Xueya Cai, Donald Y. M. Leung, Lisa A. Beck, Anna De Benedetto   +6 more
wiley   +1 more source

Medication Adherence Behavior Assessed Using a Digital Bottle Cap: Retrospective Cohort Study. [PDF]

J Med Internet Res
Nowojewski A, Elizarova O, Rutgersson A, Zarodkiewicz A, Jiang Y, Olsson A, Kelham M, Hanson J, Austin D, Jones DA, Parvaresh Rizi E, Ridderstråle W, Oldgren J, James S, Storey RF.   +14 more
europepmc   +1 more source

Power priors for latent variable mediation models under small sample sizes

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Latent variable models typically require large sample sizes for acceptable efficiency and reliable convergence. Appropriate informative priors are often required for gainfully employing Bayesian analysis with small samples. Power priors are informative priors built on historical data, weighted to account for non‐exchangeability with the ...
Lihan Chen, Milica Miočević, Carl F. Falk   +2 more
wiley   +1 more source

Dissolution-permeation approach for biopharmaceutical evaluation: a feasibility study using naproxen. [PDF]

J Pharm Pharm Sci
Sitovs A, Gurkina K, Petersone L, Mohylyuk V.   +3 more
europepmc   +1 more source

Biopharmaceutical Profiling of Herpetrione: A BCS II Properties and P-gp Substrate Guiding Nanoparticle Design. [PDF]

Pharmaceutics
Wang F, Deng X, Zhu Y, Zong X, Ma Y, Yuan H.   +5 more
europepmc   +1 more source

Accurate prediction of asparagine deamidation in biologics using advanced machine learning models. [PDF]

Brief Bioinform
Ahmed S, Swope N, Stanev V, Hofele R, WuDunn D, Jain R, Delmar J, Pouryahya M.   +7 more
europepmc   +1 more source

Pharmacokinetic and Biopharmaceutic Terminology [PDF]

Drug Intelligence & Clinical Pharmacy, 1977
openaire   +2 more sources

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

Izalontamab Brengitecan in Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Actionable Genomic Alterations Outside of Classical <i>EGFR</i> Mutations: A Phase Ib Study. [PDF]

J Clin Oncol
Zhou H, Zhao H, Hou X, Wang Y, He Z, Li Y, Ma Y, Zhao Y, Huang Y, Chen L, Xiao S, Zhu H, Zhu Y, Fang W, Zhang L, Yang Y.   +15 more
europepmc   +1 more source