Results 201 to 210 of about 30,350 (261)

Review Article: Accelerating Coeliac Disease Clinical Trials—Beyond Celiac Meeting With Industry, Academics, Patients and the FDA

Alimentary Pharmacology &Therapeutics, EarlyView.
A 2024 multi‐stakeholder meeting examined how to accelerate coeliac disease drug trials, highlighting key considerations in endpoint selection, symptom–histology alignment and feasibility. Progress requires patient‐centred trials showing symptomatic and intestinal improvement, appropriate gluten challenge, and early regulatory engagement, including ...
Lisa M. Fahey, Robert Anderson, Edwin Liu, Joseph A. Murray, Marie E. Robert, Jocelyn Anne Silvester, Kate Avery, Nelson Cheinquer, Kristie Grebe, Bhargav Tulabandula, Daniel A. Leffler, Beyond Celiac Coalition   +11 more
wiley   +1 more source

A randomized, non-inferiority phase III clinical trial of immunogenicity and safety of 5-dose and 4-dose schedules of a freeze-dried human rabies vaccine (MRC-5 cells) in participants aged 10-60. [PDF]

BMC Infect Dis
Zhao D, Zhao J, Chen X, Yuan L, Wang P, Shi L, Wang Y, Li J, Zhou L, Wu X, Yang S, Gao L.   +11 more
europepmc   +1 more source

Power priors for latent variable mediation models under small sample sizes

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Latent variable models typically require large sample sizes for acceptable efficiency and reliable convergence. Appropriate informative priors are often required for gainfully employing Bayesian analysis with small samples. Power priors are informative priors built on historical data, weighted to account for non‐exchangeability with the ...
Lihan Chen, Milica Miočević, Carl F. Falk   +2 more
wiley   +1 more source

Redefining Dendritic Cell Vaccines: Synergistically Co-priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines. [PDF]

Adv Sci (Weinh)
Xu X, Chen X, Wang J, Liu Y, Mustafa S, Diao L, Zhao R, Chi H, Hu K, Zhu J, Zhao J, Liu M.   +11 more
europepmc   +1 more source

Biopharmaceuticals for Cancer Treatment: An Update. [PDF]

Cancer Med
Nath AD, Alam Y, Mim AM, Akter M, Gani MA, Alam KMK, Alam MN.   +6 more
europepmc   +1 more source

Machine learning driven acceleration of biopharmaceutical formulation development using Excipient Prediction Software (ExPreSo). [PDF]

Comput Struct Biotechnol J
Vidal-Henriquez E, Holder T, Lee NF, Pompe C, Teese MG.   +4 more
europepmc   +1 more source

Prediction of metabolism and solubility of tablet-form drugs according to the biopharmaceutical drug disposition classification system. [PDF]

ADMET DMPK
Pushkarova Y, Zaitseva G, Bouaalam K.
europepmc   +1 more source

Silymarin and Silybin: Rejuvenating Traditional Remedies with Modern Delivery Strategies. [PDF]

Pharmaceutics
Li X, Zhu H, Wang Y, Zhang X, Yang Z, Yan X, Yu Q.   +6 more
europepmc   +1 more source

Wet Granulation as a Solidification Strategy for Converting Aqueous Nanosuspensions into Solid Dosage Forms. [PDF]

Pharmaceutics
Ragucci E, Uboldi M, Melocchi A, Serratoni M, Zema L.   +4 more
europepmc   +1 more source