Results 41 to 50 of about 101,810 (380)

Nanoformulation Development to Improve the Biopharmaceutical Properties of Fisetin Using Design of Experiment Approach

open access: yesMolecules, 2021
This study aimed to design an effective nanoparticle-based carrier for the oral delivery of fisetin (FST) with improved biopharmaceutical properties. FST-loaded nanoparticles were prepared with polyvinyl alcohol (PVA) and poly(lactic-co-glycolic acid ...
Wan-Yi Liu   +3 more
semanticscholar   +1 more source

Current situation and future development of the biopharmaceutical industry in China: A mixed-method study

open access: yesFrontiers in Pharmacology, 2022
Introduction: The biomedical industry has grown significantly both globally and in China; however, there are still challenges. This study aimed at evaluating the biopharmaceutical sector of China, in terms of ability to innovate, current sales volume ...
Ruomeng Yang   +25 more
doaj   +1 more source

Characterization and Value Assignment of a Monoclonal Antibody Reference Material, NMIJ RM 6208a, AIST-MAB

open access: yesFrontiers in Molecular Biosciences, 2022
Monoclonal antibodies have been established as the largest product class of biopharmaceuticals. Since extensive characterization is required for development and quality control of monoclonal antibody, a widely available reference material (RM) is needed.
Tomoya Kinumi   +9 more
doaj   +1 more source

A critical review of recent trends, and a future perspective of optical spectroscopy as PAT in biopharmaceutical downstream processing

open access: yesAnalytical and Bioanalytical Chemistry, 2020
As competition in the biopharmaceutical market gets keener due to the market entry of biosimilars, process analytical technologies (PATs) play an important role for process automation and cost reduction.
Laura Rolinger   +2 more
semanticscholar   +1 more source

A Market Shaping Approach for the Biopharmaceutical Industry: Governing Innovation Towards the Public Interest

open access: yesJournal of Law, Medicine & Ethics, 2021
Enhancing research and development and ensuring equitable pricing and access to cutting-edge treatments are both vital to a biopharmaceutical innovation system that works in the public interest.
M. Mazzucato, Henry Lishi Li
semanticscholar   +1 more source

Whole-cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production [PDF]

open access: yes, 2017
Many high-value added recombinant proteins, such as therapeutic glycoproteins, are produced using mammalian cell cultures. In order to optimise the productivity of these cultures it is important to monitor cellular metabolism, for example the utilisation
Ainsworth, C   +5 more
core   +1 more source

Developments and opportunities in continuous biopharmaceutical manufacturing

open access: yesmAbs, 2021
Today’s biologics manufacturing practices incur high costs to the drug makers, which can contribute to high prices for patients. Timely investment in the development and implementation of continuous biomanufacturing can increase the production of ...
Ohnmar Khanal, A. Lenhoff
semanticscholar   +1 more source

Control strategy for biopharmaceutical production by model predictive control

open access: yesBiotechnology progress (Print)
The biopharmaceutical industry is rapidly advancing, driven by the need for cutting‐edge technologies to meet the growing demand for life‐saving treatments.
T. Eslami, Alois Jungbauer
semanticscholar   +1 more source

End‐to‐end collaboration to transform biopharmaceutical development and manufacturing

open access: yesBiotechnology and Bioengineering, 2021
An ambitious 10‐year collaborative program is described to invent, design, demonstrate, and support commercialization of integrated biopharmaceutical manufacturing technology intended to transform the industry.
J. Erickson   +23 more
semanticscholar   +1 more source

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