Results 131 to 140 of about 39,175 (290)

Quality of Life Assessment of Breast Cancer Patients Undergoing Chemotherapy in Jordan: A Cross-Sectional Study

International Journal of Breast Cancer
Conclusion: The results of the study showed the impact of chemotherapy on the lives of patients and highlighted the aspects that need greater focus by healthcare providers in Jordan. In addition to providing treatment, emotional and psychological support
Sijood Janabi, Lobna Gharaibeh, Ibrahim Aldeeb, Ali Abuhaliema   +3 more
doaj   +1 more source

Synthesis, In Silico, and Biological Evaluation of Non‐Hydroxamate Benzoic Acid–Based Derivatives as Potential Histone Deacetylase Inhibitors (HDACi)

Chemistry &Biodiversity, EarlyView.
Compound A3bn exhibited strong binding affinities for HDAC2, HDAC6, and HDAC8. A3bn’s anticancer IC50 values were similar to those of SAHA. Cell death resulted from the extrinsic apoptotic pathway. Compound A3bn, a hydrophilic linker, which promotes zinc coordination, may be the cause of its increased activity across HDAC isoforms. ABSTRACT Unregulated
Nedaa A. Abd Al Rahim, Ammar A. Razzak Mahmood, Lubna H. Tahtamouni, Randa M. Bawadi, Ayah Y. Almasri, Marya A. Hamad, Nour A. Hussein, Salem R. Yasin, Abdulrahman M. Saleh   +8 more
wiley   +1 more source

Diffusional Models Useful in Biopharmaceutics

, 1967
William I. Higuchi
openalex   +1 more source

Poly(ethylene Glycol)‐Based Peptidomimetics (Pegtides) of Antimicrobial Peptides

ChemBioChem, EarlyView.
Polyethylene glycol (PEG) is commonly used to improve the pharmacokinetics and pharmacodynamics of therapeutic candidates by conjugation. Here PEG is exploited for peptidomimetic conversion of antimicrobial peptides (AMPs), as candidate antibacterial agents, by replacing their polyamide backbone. The pegtides obtained thereby can be readily synthesized
Conor Shine, John R. F. B. Connolly, Robert D. Murphy, Hazel Lafferty, Abdalmalek Alfnikh, Ned P. Buijs, Hawraa Shahrour, Nathaniel I. Martin, Eoghan O'Neill, George Amarandei, Jimmy Muldoon, Marc Maresca, Deirdre Fitzgerald‐Hughes, Marc Devocelle   +13 more
wiley   +1 more source

Biopharmaceutical Studies on Factors Affecting Rate of Absorption of Drugs. I. Absorption of Salicylamide in Micellar Solution.

, 1965
Hideo Yamada, Ryuichi Yamamoto
openalex   +2 more sources

Biopharmaceutical sector performance, 1st quarter 2000 [PDF]

, 2000

openalex   +1 more source

Fractionation of the Caspian sand goby epidermal exudates using membrane ultrafiltration and reversed-phase chromatography: an investigation on bioactivities

Scientific Reports
Bioactive peptide-based drugs have gained exceeding attention as promising treatments for infectious and oxidative-stress-related diseases, are exacerbated by the advent and spread of various multidrug-resistant bacteria and industrial lifestyles.
Mohammad Akhavan-Bahabadi, Hamed Paknejad, Aliakbar Hedayati, Mehran Habibi-Rezaei   +3 more
doaj   +1 more source

Unlocking Biomolecule Modification with Light‐Promoted Photocatalyst‐Free Approaches: Current Tools, Challenges, and Perspectives

ChemistryEurope, EarlyView.
This Perspective focuses on photocatalyst‐free, photoinduced modifications of biomolecules, emphasizing transformations mediated by electron donor–acceptor complexes. Mechanistic aspects, current limitations, and future opportunities are discussed, providing insight into the field of bioconjugation.
Milene Hornink, Maria Eduarda C. Thedy, Eugénie Romero, Gary A. Molander   +3 more
wiley   +1 more source

Biopharmaceutical sector performance, 2nd quarter 2000 [PDF]

, 2000

openalex   +1 more source

Intensification of the freeze drying process by the control of both freezing and primary drying steps [PDF]

, 2013
The problem of optimization of freeze-drying cycles is addressed, with emphasis in both freezing and primary drying steps. In particular, this study shows that the control of the nucleation event produces more uniform batches (as ice nucleation is ...
Barresi, Antonello, Bullich, R., Oddone, Irene, Pisano, Roberto   +3 more
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