Results 141 to 150 of about 17,488 (290)

Non-invasive spectroscopic methods for single-vial PAT in biopharmaceutical freeze-drying. On-line presentation at Marcus Evans 12th Biologics Formulation Development & Drug Delivery Forum June 14-15th 2021

, 2021
Geoffrey Smith
openalex   +2 more sources

Extent and Incidence of Pseudo‐Worsening of Kidney Function Due to Oral Antitumor Therapeutics in the AMBORA Cohort: An Analysis of Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
A considerable number of oral antitumor therapeutics (OAT) has the potential for causing pseudo‐worsening of kidney function (PW) due to inhibition of renal creatinine secretion, i.e., kidney function is unaffected, while creatinine‐based calculation of glomerular filtration rate (eGFR) erroneously indicates an impaired kidney function.
Michael I. Sponfeldner, Pauline Dürr, Phyllis Lensker, Katja Gessner, Lisa Cuba, Rainer Fietkau, Markus F. Neurath, Bernd Wullich, Marianne Pavel, Carola Berking, Matthias W. Beckmann, Andreas Mackensen, Frank Dörje, Martin F. Fromm   +13 more
wiley   +1 more source

Physico-chemical properties of lomefloxacin, levofloxacin and moxifloxacin relevant to Biopharmaceutics Classification System

Acta Chimica Slovenica, 2014
The aim of this investigation was to identify by in silico and in vitro methods the physico-chemical properties impact on bioavailability of three fluoroquinolones second, third and fourth generation in relation to Biopharmaceutics Classification System.
Ewa Kłosińska-Szmurło, Monika Grudzień, Katarzyna Betlejewska-Kielak, Franciszek Andrzej Pluciński, Joanna Biernacka, Aleksander Paweł Mazurek   +5 more
doaj  

Recent capillary electrophoresis applications for upstream and downstream biopharmaceutical process monitoring

, 2023
Debbie van der Burg, Leila Josefsson, Åsa Emmer, Cari Sänger van de Griend   +3 more
openalex   +1 more source

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

Clinical Pharmacology &Therapeutics, EarlyView.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout, Stefan De Buck, Jacques Gaudreault, Sébastien Jolivet, Vincent Duval, Valérie Cosson, Marie‐Laure Delporte   +6 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Correction: Lipodendriplexes mediated enhanced gene delivery: a cellular to pre-clinical investigation. [PDF]

Sci Rep
Tariq I, Ali MY, Sohail MF, Amin MU, Ali S, Bukhari NI, Raza A, Pinnapireddy SR, Schäfer J, Bakowsky U.   +9 more
europepmc   +1 more source

The cause relation in biopharmaceutical corpora: English and French patterns for knowledge extraction.

, 2002
Elizabeth Marshman
openalex   +1 more source

Market Perceptions of ESG Reputational Risk in the US Pharmaceutical Industry

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Negative ESG‐related reputational events generate significant corporate risks, particularly within sensitive sectors such as the pharmaceutical industry. Using novel reputational data, this research investigates investor perceptions of the consequences of experienced ESG breaches among US pharmaceutical firms.
Erdinc Akyildirim, Shaen Corbet, Jose Antonio Muñiz, Frank Scrimgeour   +3 more
wiley   +1 more source

Factors influencing production of anti-drug antibodies against biopharmaceuticals in rheumatoid arthritis patients

, 2018
Hiroko Shibata, Kazuko Nishimura, Chizuru Miyama, Akiko Ishii‐Watabe, Yoshimi Okamoto‐Uchida, Yoshiro Saito, Shinichi Kawai, Soichi Yamada, Toshihiro Nanki   +8 more
openalex   +2 more sources