Results 151 to 160 of about 39,175 (290)
Clinical Pharmacology &Therapeutics, EarlyView.Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu +21 more
wiley +1 more source
Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization
Clinical Pharmacology &Therapeutics, EarlyView.Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su +6 more
wiley +1 more source
Computational knowledge integration in biopharmaceutical research [PDF]
, 2003 D. Ficenec
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Clinical Pharmacology &Therapeutics, EarlyView.Since 2016, the China National Medical Products Administration (NMPA) has reformed its drug registration classification rules and defines the innovative drugs as new drugs that have not been marketed domestically and overseas. This study sought to systematically evaluate the characteristics of the innovative drugs approved in China. The cross‐sectional
Xingyue Zhu, Die Xiao
wiley +1 more source
Development of the second‐order derivative UV spectrophotometric method for direct determination of paracetamol in urine intended for biopharmaceutical characterisation of drug products [PDF]
, 2003 Jelena Parojčić +4 more
openalex +1 more source
Switchable Intersystem Crossing (sISC) in Organic Dyes: Unlocking Dynamic Photonic Properties
ChemPhotoChem, EarlyView.This Concept article introduces switchable intersystem crossing (sISC) as an emerging design strategy for functional dyes capable of reversibly modulating fluorescence and triplet state formation in response to environmental stimuli. Key design approaches and underlying mechanisms are discussed, alongside representative examples of sISC dyes and their ...
Mikhail A. Filatov, Metodej Dvoracek
wiley +1 more source
A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy [PDF]
, 2004 Michael Lindenbaum +20 more
openalex +1 more source