Rapid Profiling, Fingerprinting, and Speciation of Poloxamer 188 in Biotherapeutic Drug Production Using Comprehensive Liquid Chromatography-Charge Reduction Mass Spectrometry Analysis. [PDF]
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Correction to "Expanding the Genetic and Clinical Spectrum of SLC25A42 Associated Disorders and Testing of Pantothenic Acid to Improve CoA Level In Vitro". [PDF]
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Exploring Antibiotic Resistance Patterns in <i>Escherichia coli</i> Isolates from Urinary Tract Infections: A Retrospective Study. [PDF]
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Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference. [PDF]
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<i>In Vitro</i> Drug Release Kinetics and Antioxidant Activity of Metformin-Loaded Niosomes. [PDF]
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Erratum: Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, Systemic Immune Inflammation Index and Efficacy of Remote Ischemic Conditioning in Acute Ischemic Stroke: A Post Hoc Exploratory Analysis of the RICAMIS Study [Corrigendum]. [PDF]
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Biopharmaceuticals are primarily therapeutic proteins developed to perform specific functions by acting on the disease pathophysiology. Compared with low-molecular chemically synthesized drugs, production of biopharmaceuticals is much more complex and routes of administration and pharmacokinetics differ.
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The rapid maturation of the field of biopharmaceutical formulation is the result of the simultaneous development of a thermodynamic mechanism for protein-solvent interaction and identification of natural chemicals employed by nature to stabilize proteins in response to environmental stresses.
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