Results 81 to 90 of about 39,175 (290)

Determining the solubility and crystal form of clenbuterol in thin films of eudragit NE30D [PDF]

, 1992
The solubility of the drug clenbuterol in thin films of surfactant-free Eudragit NE30D has been measured. Light microscopy and differential scanning calorimetry were supplemented by a technique based on measurement of the rate of drug release from the ...
Göpferich, Achim, Lee, Geoffrey
core   +1 more source

Assessment of “Sameness” and/or Differences between Marketed Creams Containing Miconazole Nitrate Using a Discriminatory in vitro Release Testing (IVRT) Method

Scientia Pharmaceutica, 2020
In vitro release testing (IVRT) provides an efficient method for the evaluation of drug release from semi-solid formulations. The aim of this research was to develop and validate a discriminatory IVRT system using vertical diffusion cells (VDCs) to ...
Potiwa Purazi, Seeprarani Rath, Ashmita Ramanah, and Isadore Kanfer   +3 more
doaj   +1 more source

Hierarchically Porous Multiphase Si‐Based Ceramics with Synergistic Electromagnetic Wave Absorption Mechanisms

Advanced Science, EarlyView.
A novel multiphase Si‐based ceramic material with hierarchical porosity is devised via one‐step etching activation of carbon‐rich polycarbosilane ceramics. Integrating free carbon, SiC crystals, amorphous SiOC, and engineered porosity, the material surprisingly achieves exceptional electromagnetic absorption performance, offering new insights into the ...
Jiaojiao Jiang, Xiaomei Deng, Sihan Li, Xiaojun Zeng, Chunxiao Wu, Chao Yang   +5 more
wiley   +1 more source

Relationship Between Characteristics of Medications and Drug-Induced Liver Disease Phenotype and Outcome [PDF]

, 2014
Background & Aims: It is not known if specific characteristics of medication are associated with type of drug-induced liver injury (DILI) or outcome.
Chalasani, Naga, Fontana, Robert J., Ghabril, Marwan, Gotur, Raghavender, Gu, Jiezhun, Kosinski, Andrzej S., Reddy, K. Rajender, Serrano, Jose, Vuppalanchi, Raj   +8 more
core   +1 more source

Linker‐regulated Imine‐based Covalent Organic Frameworks Enable Dual‐Mode Fluorescence Emission as Stable Internal Reference Signal

Aggregate, EarlyView.
Imine‐based covalent organic frameworks achieve dual fluorescence through synergistic aggregation‐induced emission and excited‐state intramolecular proton transfer effects, suppressing aggregation‐caused quenching and enhancing emission. This intrinsic signal functions as an internal reference, while integration with Sc3⁺ sensitization constructs ...
Xuequan Jing, Peihai Ju, Huimin Xie, Meina Guo, Huifeng Zeng, Hongdong Yu, Kang Hu, Tinggang Li, Yinhua Wan, Hongbin Cao   +9 more
wiley   +1 more source

The use of heat and chemical penetration enhancers to increase the follicular delivery of erythromycin to the skin [PDF]

, 2019
Copyright © 2019. Published by Elsevier B.V.The effect of heat on the follicular absorption of drugs into the skin has not previously been investigated.
Akomeah, Alberti, Baden, Butcher, Cada, Coldman, Edwards, F. Caserta, FDA, Feldmann, Goh, Higuchi, ICH, Q2(R1), Kim, Kligman, Liu, M.B. Brown, McAuley, McAuley, Minson, Motwani, Motwani, OECD, Oliveira, Otberg, Park, Piazza, Pierard, Rancan, Saar, Santos, Sato, Shergill, Szabo, Teichmann, Toll, Twist, W.J. McAuley, Wood, Wood, Wood, Yarnitsky, Zhang   +42 more
core   +2 more sources

Establishing an innovative carbohydrate metabolic pathway for efficient production of 2-keto-l-gulonic acid in Ketogulonicigenium robustum initiated by intronic promoters

Microbial Cell Factories, 2018
Background 2-Keto-l-gulonic acid (2-KGA), the precursor of vitamin C, is currently produced by two-step fermentation. In the second step, l-sorbose is transformed into 2-KGA by the symbiosis system composed of Ketogulonicigenium vulgare and Bacillus ...
Cai-Yun Wang, Ye Li, Zi-Wei Gao, Li-Cheng Liu, Meng-Yue Zhang, Tian-Yuan Zhang, Chun-Fu Wu, Yi-Xuan Zhang   +7 more
doaj   +1 more source

A systematic screening of neural network‐based hybrid models of adsorption in chromatography processes

AIChE Journal, EarlyView.
Abstract In this study, various adsorption models using neural networks were developed and integrated into a mechanistic chromatography transport model, resulting in hybrid models. A systematic screening of 10 different hybrid model structures was performed to find the optimal balance between mechanistic and data‐driven components in modeling ...
Jesper Frandsen, Vinicius V. Santana, Peter Jul‐Rasmussen, Idelfonso B.R. Nogueira, Jakob K. Huusom, Krist V. Gernaey, Jens Abildskov   +6 more
wiley   +1 more source

Quantification of Cell Subpopulations, Fractions of Dead Cells and Debris in Cell Suspensions by Laser Diffractometry [PDF]

, 1992
Laser diffractometry was employed for size analysis in liver cell and blood cell suspensions to assess its suitability for characterizing cell populations.
Blunk, Torsten, Müller, R. H., Rudt, S.
core  

The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation

Cells, 2020
NSIAD is a rare X-linked condition, caused by activating mutations in the AVPR2 gene coding for the vasopressin V2 receptor (V2R) associated with hyponatremia, despite undetectable plasma vasopressin levels.
Marianna Ranieri, Maria Venneri, Tommaso Pellegrino, Mariangela Centrone, Annarita Di Mise, Susanna Cotecchia, Grazia Tamma, Giovanna Valenti   +7 more
doaj   +1 more source