Results 31 to 40 of about 690,369 (235)

Modernizing the NEURON Simulator for Sustainability, Portability, and Performance

open access: yesFrontiers in Neuroinformatics, 2022
The need for reproducible, credible, multiscale biological modeling has led to the development of standardized simulation platforms, such as the widely-used NEURON environment for computational neuroscience. Developing and maintaining NEURON over several
Omar Awile   +18 more
doaj   +1 more source

Unraveling the unsustainability spiral in sub-Saharan Africa: an agent based modelling approach [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2007
Sub-Saharan Africa is trapped in a complex unsustainability spiral with demographic, biophysical, technical and socio-political dimensions. Unravelling the spiral is vital to perceive which policy actions are needed to reverse it and initiate sustainable
Joep A. van den Broek   +3 more
doaj  

Engineering improved measurement and actuation for nanoscale biophysics

open access: yesBiophysical Reviews, 2020
This commentary profiles the research interests of my recently established research group at The University of Chicago, as well as my own research trajectory and contributions to the field of nanoscale biophysics. I describe here certain open challenges of interest that drive my group's current research efforts, along with my past efforts that have ...
openaire   +3 more sources

Techniques of Geoprocessing via Cloud in Google Earth Engine Applied to Vegetation Cover and Land Use and Occupation in the Brazilian Semiarid Region

open access: yesGeographies, 2022
Thematic maps of land cover and use can assist in the environmental monitoring of semiarid regions, mainly due to the advent of climate change, such as drought, and pressures from anthropic activities, such as the advance of urban areas.
Jhon Lennon Bezerra da Silva   +6 more
doaj   +1 more source

Variation of Engine Performance and Emissions using Ethanol Blends [PDF]

open access: yes, 2010
The limited fossil fuel resources along with the increased public concerns about pollution levels have increased the need for alternative fuels for use in internal combustion engines.
Abuhabaya, Abdullah, Fieldhouse, John D.
core   +4 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

New perspectives on Web search engine research [PDF]

open access: yes, 2012
Purpose–The purpose of this chapter is to give an overview of the context of Web search and search engine-related research, as well as to introduce the reader to the sections and chapters of the book.
Lewandowski, Dirk
core  

Combustion Characteristics of CI Engine Running with Biodiesel Blends [PDF]

open access: yes, 2011
Biodiesel is one of the promising renewable, alternative and environmentally friendly biofuels that can be used in diesel engine with little or no modification in the engine.
Gu, Fengshou   +3 more
core   +5 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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