Results 41 to 50 of about 690,369 (235)

Sub-series 2: Publications

open access: yes, 1983
Newsletter discussing updates, news, and events for the Model Engine Collectors' Association as well as topics of interest to ...
Model Engine Collectors' Association
core   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Comparative Analysis of Urban Land Use Sustainability Using a Cloud-Based Decision Support Framework with Rule-Based Spatial Analytics: The Cases of Barcelona and Izmir

open access: yesLand
This study presents a comparative analysis of urban land-use sustainability in Barcelona and Izmir using a four-tier Decision Support Framework (DSF) supported by automated Google Earth Engine workflows.
Vuslat Salalı
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Revealing physical properties of gastric adenocarcinoma cells with two distinct morphologies linking to preferential cellular migration and proliferation

open access: yesCell Communication and Signaling
Mechanobiology has played significant roles in guiding and regulating cellular activities, such as morphogenesis, organogenesis, wound healing. Inter-/intracellular force or stiffness as an engine induced cell to reshape their morphologies leading to ...
Dong Wang, Shinji Watanabe, Linhao Sun
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The acoustics of racing engine intake systems [PDF]

open access: yes, 2004
Naturally aspirated racing engines have tuned intake systems and can now achieve volumetric efficiencies in excess of 125% and peak engine speeds in excess of 18,000 rev/min.
Harrison, M. F., Dunkley, A.
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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