Results 121 to 130 of about 1,181,476 (312)

A Modular Microfluidic System to Generate Gradient Hydrogels with Simple‐to‐Complex Stiffness Profiles for Mechanobiology

Advanced Materials Technologies, EarlyView.
This work introduces a universal approach for fabricating stiffness gradient hydrogels with diverse stiffness ranges and gradient profiles. Gradient formation is achieved by precisely controlling the thermal landscape within a microfluidic system, which drives thermophoretic redistribution of precursor components in solution.
Shin Wei Chong, Jameel Sardharwalla, Gweneth Sofia P. Masonsong, Joshua Cosgrove, Anthony Katselas, Isaac J. Gresham, Marcela M. M. Bilek, Yi Shen, Chiara Neto, Daniele Vigolo   +9 more
wiley   +1 more source

Transition‐Metal Azo Schiff Base Complexes: Nonlinear Optics Across Solutions, Thin Films and Nanocomposites

Advanced Optical Materials, EarlyView.
The excitation of a transition‐metal azo Schiff‐base complex with a 1064 nm laser induces a series of nonlinear optical effects. These effects include the second harmonic generation at 532 nm and third harmonic generation at 355 nm. This process demonstrates the potential of the complex for high‐order nonlinear optical applications. Abstract This paper
Karolina Waszkowska, Mark Busch, Siham Slassi, Amina Amine, Abdelkrim El‐Ghayoury, Janusz Strzelecki, Anna Zawadzka, Andriy V. Kityk, Patrick Huber, Bouchta Sahraoui   +9 more
wiley   +1 more source

Solvation free energy of light alkanes in polar and amphiphilic environments

Bibechana, 2018
Computer simulations of molecular models are powerful technique that have improved the under- standing of many biochemical phenomena. The method is frequently applied to study the motions of biological macromolecules such as protein and nucleic acids ...
Sunil Pokharel, Shyam Prakash Khanal, N P Adhikari   +2 more
doaj   +1 more source

Label‐Free Characterization of Lipid Interfaces Using Plasmonic Gold Nanorods as Optically Active Nanosensors

Advanced Optical Materials, EarlyView.
A label‐free plasmonic nanosensor platform is presented based on single gold nanorods for the nanometric characterization of lipid interfaces. By correlating optical scattering signals with membrane packing and refractive index, this approach enables the detection of gel‐to‐fluid transitions in lipid interfaces, offering a robust, high‐resolution ...
Alfredo Casasnovas‐Melián, Natalia Robles‐Anda, Lucía Labrador‐Páez, Florian D. Kofler, Jaime Hinojosa‐Platero, Elena Junquera, Miguel A. Sacristán, Iván López‐Montero, Ainhoa Collada, Antonio Cruz, Jesús Pérez‐Gil, Rubén Ahijado‐Guzmán, Andrés Guerrero‐Martínez   +12 more
wiley   +1 more source

Current advances in mathematical modeling of anti-cancer drug penetration into tumor tissues

Frontiers in Oncology, 2013
Delivery of anti-cancer drugs to tumor tissues, including their interstitial transport and cellular uptake, is a complex process involving various biochemical, mechanical, and biophysical factors.
MunJu eKim, Robert J Gillies, Katarzyna Anna Rejniak   +2 more
doaj   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Physics of Selective Targeting of Cancer Cells by Magnetoelectric Nanoparticles: Exploring the Role of Conductivity and Capacitance in Tumor‐Specific Attraction

Advanced Theory and Simulations, EarlyView.
Magnetoelectric nanoparticles exploit cancer cells' electrical vulnerabilities—altered membrane charge and higher capacitance—to achieve tumor‐specific targeting without bioreagents. MATLAB simulations reveal how electromagnetic forces create targeting specificity, while external magnetic fields enhance precision. This may enable wirelessly controlled,
Max Shotbolt, John Bryant, Ping Liang, Sakhrat Khizroev   +3 more
wiley   +1 more source

Utilizing Causal Network Markers to Identify Tipping Points ahead of Critical Transition

Advanced Science, EarlyView.
The study proposes a causal network markers (CNMs) framework to identify early‐warning signals preceding critical transitions. It validates CNMs on various computational benchmark models and real‐world datasets, demonstrating higher accuracy and flexibility compared to existing approaches.
Shirui Bian, Zezhou Wang, Siyang Leng, Wei Lin, Jifan Shi   +4 more
wiley   +1 more source

Surface Interactions and Mechanical Properties Shaping Biofilm Dynamics in S. aureus and P. aeruginosa

Journal of Global Antimicrobial Resistance
This study comprehensively investigates biofilm formation, and exploring its various biophysical properties like adhesion, surface roughness, cell stiffness, and cell surface hydrophobicity. The study is focused on five foodborne biofilm-positive strains
Shaista Urooj
doaj   +1 more source