Results 121 to 130 of about 1,142,090 (245)
Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy
Advanced Science, EarlyView.This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier +16 more
wiley +1 more source
Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
CREATING EDUCATIONAL VIDEOS IN THE PROCESS OF STUDENTS’ PROJECT ACTIVITY
Неперервна професійна освіта: теорія та практикаThis article explores the role of digital visualizations in fostering motivation among students of medical (pharmaceutical) higher education institutions to study physical and mathematical disciplines. The main focus is on creating dynamic visualizations
Halyna Khrapiichuk +2 more
doaj +1 more source
Towards a corpuscular model of optical phenomena [PDF]
, 2011 This thesis presents a collection of event-by-event models that simulate fundamental optical experiments. The simulation approach is completely based on the experimental facts.
Jin, Fengping, Jin, Fengping,
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Advanced Science, EarlyView.A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen +5 more
wiley +1 more source
A Holocamera for Studies of Biophysical Phenomena
, 1974 Anthony N. Gentile's thesis positing the feasibility of the holography of biophysical phenomena.This thesis is being archived as a Digitized Shelf Copy for campus access to current students and staff only.
Gentile, Anthony N.
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Advanced Science, EarlyView.This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka +3 more
wiley +1 more source
A physics-informed eikonal model for simulating arrhythmias in the human heart in real-time
Nature CommunicationsPersonalized computational models of cardiac electrophysiology, referred to as cardiac digital twins, are considered a key technology for realizing precision cardiology by tailoring therapies to individual patients.
Thomas G. Schrotter +6 more
doaj +1 more source
Early detection of action potential duration alternans using an autoregressive model
, 2012 Annual Meeting of the Biophysical Society, San Diego ...
De Lange, E +4 more
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