Results 31 to 40 of about 1,142,090 (245)

A kinetic model describing the processivity of Myosin-V [PDF]

, 2005
The precise details of how myosin-V coordinates the biochemical reactions and mechanical motions of its two head elements to engineer effective processive molecular motion along actin filaments remain unresolved.
Turner, Matthew S., Turner, MS, Skau, Karl I., Skau, KI, Hoyle, Rebecca B., Hoyle, RB   +5 more
core   +1 more source

The meso scale as a frontier in interdisciplinary modeling of sustainability from local to global scales

Environmental Research Letters, 2023
Achieving sustainable development requires understanding how human behavior and the environment interact across spatial scales. In particular, knowing how to manage tradeoffs between the environment and the economy, or between one spatial scale and ...
Justin Andrew Johnson, Molly E Brown, Erwin Corong, Jan Philipp Dietrich, Roslyn C Henry, Patrick José von Jeetze, David Leclère, Alexander Popp, Sumil K Thakrar, David R Williams   +9 more
doaj   +1 more source

A Review of Biophysical Models of Marine Larval Dispersal [PDF]

, 2019
Larval dispersal is arguably the most important but least understood demographic process in the sea. The likelihood of a larva dispersing from its birthplace to successfully recruit in another location is the culmination of many intrinsic and extrinsic
Stephen E. Swearer, Eric A. Treml, Swearer, Stephen E., Shima, Jeffrey S., Treml, Eric A., Jeffrey S. Shima   +5 more
core   +1 more source

Micropatterning of single endothelial cell shape reveals a tight coupling between nuclear volume in G1 and proliferation [PDF]

, 2008
Shape-dependent local differentials in cell proliferation are considered to be a major driving mechanism of structuring processes in vivo, such as embryogenesis, wound healing, and angiogenesis.
Farré, Ramon, Roca-Cusachs Soulere, Pere, Farré Ventura, Ramon, Samitier, Josep, Alcaraz Casademunt, Jordi, Roca-Cusachs, Pere, Samitier i Martí, Josep, Navajas, Daniel, Sunyer, Raimon, Navajas Navarro, Daniel, Alcaraz, Jordi   +10 more
core   +1 more source

The development of cooperative channels explains the maturation of hair cell’s mechanotransduction [PDF]

, 2019
Hearing relies on the conversion of mechanical stimuli into electrical signals. In vertebrates, this process of mechano-electrical transduction (MET) is performed by specialized receptors of the inner ear, the hair cells.
Risler, Thomas, Kozlov, Andrei S, Gianoli, Francesco, Kozlov, Andrei,   +3 more
core   +1 more source

Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy

Radiation Oncology, 2019
Background Helium (4He) ion beam therapy provides favorable biophysical characteristics compared to currently administered particle therapies, i.e., reduced lateral scattering and enhanced biological damage to deep-seated tumors like heavier ions, while ...
Stewart Mein, Ivana Dokic, Carmen Klein, Thomas Tessonnier, Till Tobias Böhlen, Guiseppe Magro, Julia Bauer, Alfredo Ferrari, Katia Parodi, Thomas Haberer, Jürgen Debus, Amir Abdollahi, Andrea Mairani   +12 more
doaj   +1 more source

Unveiling molecular interactions that stabilize bacterial adhesion pili

, 2022
Adhesion pili assembled by the chaperone-usher pathway are superelastic helical filaments on the surface of bacteria, optimized for attachment to target cells.
Dahlberg, Tobias,, Bullitt, Esther,, Baker, Joseph,, Baker, Joseph, Dahlberg, Tobias, Andersson, Magnus,, Bullitt, Esther, Andersson, Magnus   +7 more
core   +1 more source

Abortive and propagating intracellular calcium waves: analysis from a hybrid model. [PDF]

PLoS ONE, 2015
The functional properties of inositol(1,4,5)-triphosphate (IP3) receptors allow a variety of intracellular Ca(2+) phenomena. In this way, global phenomena, such as propagating and abortive Ca(2+) waves, as well as local events such as puffs, have been ...
Nara Guisoni, Paola Ferrero, Carla Layana, Luis Diambra   +3 more
doaj   +1 more source

A biophysical approach to the optimisation of dendritic-tumour cell electrofusion

, 2022
S.829-839Electrofusion of tumour and dendritic cells (DCs) is a promising approach for production of DC-based anti-tumour vaccines. Although human DCs are well characterised immunologically, little is known about their biophysical properties, including ...
Reuss, R., Sukhorukov, V.L., Müller, K.J., Karpas, A., Steinbach, A., Katsen-Globa, A., Geßner, P., Zimmermann, H., Zimmermann, U., Fehrmann, S., Endter, J.M.   +10 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source