Results 41 to 50 of about 109,084 (285)

Abortive and propagating intracellular calcium waves: analysis from a hybrid model. [PDF]

PLoS ONE, 2015
The functional properties of inositol(1,4,5)-triphosphate (IP3) receptors allow a variety of intracellular Ca(2+) phenomena. In this way, global phenomena, such as propagating and abortive Ca(2+) waves, as well as local events such as puffs, have been ...
Nara Guisoni, Paola Ferrero, Carla Layana, Luis Diambra   +3 more
doaj   +1 more source

Functional advantages offered by many-body coherences in biochemical systems

, 2017
Quantum coherence phenomena driven by electronic-vibrational (vibronic) interactions, are being reported in many pulse (e.g. laser) driven chemical and biophysical systems.
Acevedo, O. L., Gomez-Ruiz, F. J., Johnson, N. F., Quiroga, L., Rodriguez, F. J.   +4 more
core   +1 more source

Developing a conceptual model of marine farming in New Zealand [PDF]

, 2009
Survey and Geographic Information System (GIS) data analysis describes the relative influence of biophysical and human variables on site choices made by marine farmers in New Zealand.
Brabyn, Lars, Rennie, Hamish Gordon, White, Roger   +2 more
core   +2 more sources

The Whole is Greater Than the Sum of Its Parts: Large-scale Phenomena Arising from Small-scale Biophysical Processes

Integrative And Comparative Biology, 2023
Synopsis The symposium “Large-scale biological phenomena arising from small-scale biophysical processes” at the SICB 2023 Annual General Meeting focused on the cross-disciplinary exploration of emergent phenomena in biology. Interactions between cells or organisms at small scales within a system can govern patterns occurring at larger ...
Wheeler, J. D., Chan, Kit Yu Karen
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Characterization of Sensory-Motor Behavior Under Cognitive Load Using a New Statistical Platform for Studies of Embodied Cognition

Frontiers in Human Neuroscience, 2018
The field of enacted/embodied cognition has emerged as a contemporary attempt to connect the mind and body in the study of cognition. However, there has been a paucity of methods that enable a multi-layered approach tapping into different levels of ...
Jihye Ryu, Elizabeth B. Torres
doaj   +1 more source

Governing in the Anthropocene: What Future Systems Thinking in Practice? [PDF]

, 2016
The revealing and concealing features of the metaphor ‘earth as Anthropocene’ are explored in an inquiry that asks: In the Anthropocene what possible futures emerge for systems thinking in practice? Framing choice, so important yet so poorly realised, is
Alstyne, Armitage, Ashby, Baird, Baird, Bateson, Beer, Biermann, Bommel, Boulding, Checkland, Checkland, Checkland, Checkland, Cook, Crutzen, Hubert, Ison, Ison, Ison, Ison, Ison, Ison, Ison, Ison, Jasanoff, Jones, Lakoff, Lakoff, Lakoff, Lakoff, Larsen, LEARN, Lourdes Melo Zurita, Malm, McClintock, McClintock, Meadows, Micklethwait, Moll, Norgaard, Open University, Powell, Russell, Russell, Sankaran, Schön, Steirlin, Steyaert, Stowell, Straw, Thompson, Tingle, Tsien, Westberg, Wiener   +55 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Comparing parameter-reduction methods on a biophysical model of an auditory hair cell

Physical Review Research
Biophysical models describing complex cellular phenomena typically include systems of nonlinear differential equations with many free parameters. While experimental measurements can fix some parameters, those describing internal cellular processes ...
Joseph M. Marcinik, Martín A. Toderi, Dolores Bozovic   +2 more
doaj   +1 more source

Ultrafast Fluorescence Spectroscopy via Upconversion and Its Applications in Biophysics

Molecules, 2021
In this review, the experimental set-up and functional characteristics of single-wavelength and broad-band femtosecond upconversion spectrophotofluorometers developed in our laboratory are described.
Simin Cao, Haoyang Li, Zenan Zhao, Sanjun Zhang, Jinquan Chen, Jianhua Xu, Jay R. Knutson, Ludwig Brand   +7 more
doaj   +1 more source