Results 61 to 70 of about 1,142,090 (245)

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Extension of a multiphase tumour growth model to study nanoparticle delivery to solid tumours.

PLoS ONE, 2020
One of the main challenges in increasing the efficacy of conventional chemotherapeutics is the fact that they do not reach cancerous cells at a sufficiently high dosage.
Barbara Wirthl, Johannes Kremheller, Bernhard A Schrefler, Wolfgang A Wall   +3 more
doaj   +1 more source

Structure and dynamics of ER: minimal networks and biophysical constraints. [PDF]

, 2014
Copyright © 2014 Biophysical Society. Published by Elsevier Inc. All rights reserved.PMCID: PMC4129489The endoplasmic reticulum (ER) in live cells is a highly mobile network whose structure dynamically changes on a number of timescales.
Lin, Congping, Ashwin, Peter, Lin, C., Ashwin, P., Sparkes, I., Zhang, Yiwei, Sparkes, Imogen   +6 more
core   +1 more source

Plasma Gelation as an Overlooked Determinant of Transfection Efficiency in Protein Corona‐Coated Lipid Nanoparticles: Implications for In Vitro–In Vivo Translation

Advanced Healthcare Materials, EarlyView.
Upon contact with plasma, lipid nanoparticles (LNPs) rapidly acquire a protein corona (PC) that redefines their biological identity. In calcium‐containing environments, these coronated particles trigger the formation of a gel‐like plasma network, profoundly altering their transport properties and reducing their effective availability.
Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Daniela Pozzi, Junbiao Wang, Augusto Amici, Cristina Marchini, Chiara Cassone, Alessandra Zingoni, Fabrizio Marra, Luca Buccini, Francesco Mura, Valentina De Lorenzi, Francesco Cardarelli, Giulio Caracciolo   +14 more
wiley   +1 more source

Web-based computational chemistry education with CHARMMing II: Coarse-grained protein folding. [PDF]

PLoS Computational Biology, 2014
A lesson utilizing a coarse-grained (CG) Gō-like model has been implemented into the CHARMM INterface and Graphics (CHARMMing) web portal (www.charmming.org) to the Chemistry at HARvard Macromolecular Mechanics (CHARMM) molecular simulation package ...
Frank C Pickard, Benjamin T Miller, Vinushka Schalk, Michael G Lerner, H Lee Woodcock, Bernard R Brooks   +5 more
doaj   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Long-term potentiation mechanism of biological postsynaptic activity in neuro-inspired halide perovskite memristors

Neuromorphic Computing and Engineering, 2023
Perovskite memristors have emerged as leading contenders in brain-inspired neuromorphic electronics. Although these devices have been shown to accurately reproduce synaptic dynamics, they pose challenges for in-depth understanding of the underlying ...
Enrique Hernández-Balaguera, Laura Munoz-Díaz, Agustín Bou, Beatriz Romero, Baurzhan Ilyassov, Antonio Guerrero, Juan Bisquert   +6 more
doaj   +1 more source

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

Multiscale modeling approaches in biomolecular physics

Advances in Physics: X
Biomolecular function arises from phenomena spanning several lengths and time scales, from electronic rearrangements and charge transfer to conformational dynamics and cellular-scale processes.
Luca Gerhards, Jonathan Hungerland, Fabian Schuhmann, Andrei Y. Kostritski, Vladimir Bačić, Beatrice Geiger, Adrià Bravo Vidal, Weria Pezeshkian, Frank Ortmann, Christian Wiebeler, Ilia A. Solov’yov   +10 more
doaj   +1 more source

Biophysics and vegetation cover change: a process-based evaluation framework for confronting land surface models with satellite observations [PDF]

Earth System Science Data, 2018
Land use and land cover change (LULCC) alter the biophysical properties of the Earth's surface. The associated changes in vegetation cover can perturb the local surface energy balance, which in turn can affect the local climate. The sign and magnitude
G. Duveiller, G. Forzieri, E. Robertson, W. Li, G. Georgievski, P. Lawrence, A. Wiltshire, P. Ciais, J. Pongratz, S. Sitch, A. Arneth, A. Cescatti   +11 more
doaj   +1 more source