Results 51 to 60 of about 109,084 (285)

Traveling waves of excitation in neural field models [PDF]

open access: yes, 2002
Field models provide an elegant mathematical framework to analyze large-scale patterns of neural activity. On the microscopic level, these models are usually based on either a firing-rate picture or integrate-and-fire dynamics. This article shows that in
Cremers, Daniel, Herz, Andreas V. M.
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio   +8 more
wiley   +1 more source

Formation of Stable Amorphous Calcium Phosphate and Collagen Assemblies by a Versatile Spray‐Drying Approach

open access: yesAdvanced Functional Materials, EarlyView.
Amorphous calcium phosphate (ACP) microparticles with long‐term and thermal stability are prepared with or without collagen using a scalable one‐pot spray‐drying process. Under simulated physiological conditions, they crystallize into biomimetic bone mineral and, when combined with collagen, form extrudable, fibrillar bone‐like 3D constructs.
Camila Bussola Tovani   +13 more
wiley   +1 more source

A method for modeling growth of organs and transplants based on the general growth law: application to the liver in dogs and humans. [PDF]

open access: yesPLoS ONE, 2014
Understanding biological phenomena requires a systemic approach that incorporates different mechanisms acting on different spatial and temporal scales, since in organisms the workings of all components, such as organelles, cells, and organs interrelate ...
Yuri K Shestopaloff, Ivo F Sbalzarini
doaj   +1 more source

Method for finding metabolic properties based on the general growth law. Liver examples. A General framework for biological modeling

open access: yes, 2014
We propose a method for finding metabolic parameters of cells, organs and whole organisms, which is based on the earlier discovered general growth law.
Shestopaloff, Yuri K.
core   +2 more sources

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

Biophysical Interactions in Fragmented Marine Canopies: Fundamental Processes, Consequences, and Upscaling

open access: yesFrontiers in Marine Science, 2019
Spatial fragmentation is a near-ubiquitous characteristic of marine canopies. Biophysical interactions with fragmented canopies are multi-faceted and have many significant implications at multiple scales.
Andrew M. Folkard
doaj   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

open access: yesAdvanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter   +5 more
wiley   +1 more source

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