Results 61 to 70 of about 1,099,223 (288)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
A method for modeling growth of organs and transplants based on the general growth law: application to the liver in dogs and humans. [PDF]
PLoS ONE, 2014 Understanding biological phenomena requires a systemic approach that incorporates different mechanisms acting on different spatial and temporal scales, since in organisms the workings of all components, such as organelles, cells, and organs interrelate ...
Yuri K Shestopaloff, Ivo F Sbalzarini
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Joint Gaussian Processes for Biophysical Parameter Retrieval [PDF]
IEEE Transactions on Geoscience and Remote Sensing, 2017 Solving inverse problems is central in geosciences and remote sensing. The radiative transfer models (RTMs) represent mathematically the physical laws that rule the phenomena in remote sensing applications (forward models). The numerical inversion of the
D. Svendsen +4 more
semanticscholar +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Frontiers in Marine Science, 2019 Spatial fragmentation is a near-ubiquitous characteristic of marine canopies. Biophysical interactions with fragmented canopies are multi-faceted and have many significant implications at multiple scales.
Andrew M. Folkard
doaj +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection
BioMedical Engineering OnLine, 2007 Background Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and ...
Roberts Stephen J +4 more
doaj +1 more source
Extension of a multiphase tumour growth model to study nanoparticle delivery to solid tumours.
PLoS ONE, 2020 One of the main challenges in increasing the efficacy of conventional chemotherapeutics is the fact that they do not reach cancerous cells at a sufficiently high dosage.
Barbara Wirthl +3 more
doaj +1 more source