Results 71 to 80 of about 1,099,223 (288)
Web-based computational chemistry education with CHARMMing II: Coarse-grained protein folding. [PDF]
A lesson utilizing a coarse-grained (CG) Gō-like model has been implemented into the CHARMM INterface and Graphics (CHARMMing) web portal (www.charmming.org) to the Chemistry at HARvard Macromolecular Mechanics (CHARMM) molecular simulation package ...
Frank C Pickard+5 more
doaj +1 more source
The rapid development of urban areas can potentially alter hydro-meteorological fluxes and lead to the Urban Heat Island (UHI) phenomenon. In this study, UHI intensity and its driving factors were estimated using the Community Land Model (CLM) in cities ...
Ressy Fitria+3 more
semanticscholar +1 more source
Certain G-quadruplex forming guanine-rich oligonucleotides (GROs), including AS1411, are endowed with cancer-selective antiproliferative activity. They are known to bind to nucleolin protein, resulting in the inhibition of nucleolin-mediated phenomena ...
A. Ogloblina+9 more
semanticscholar +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
Perovskite memristors have emerged as leading contenders in brain-inspired neuromorphic electronics. Although these devices have been shown to accurately reproduce synaptic dynamics, they pose challenges for in-depth understanding of the underlying ...
Enrique Hernández-Balaguera+6 more
doaj +1 more source
Hierarchical self-assembly of a reflectin-derived peptide
Reflectins are a family of intrinsically disordered proteins involved in cephalopod camouflage, making them an interesting source for bioinspired optical materials.
Ana Margarida Gonçalves Carvalho Dias+20 more
doaj +1 more source
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song+8 more
wiley +1 more source
Biophysics and vegetation cover change: a process-based evaluation framework for confronting land surface models with satellite observations [PDF]
Land use and land cover change (LULCC) alter the biophysical properties of the Earth's surface. The associated changes in vegetation cover can perturb the local surface energy balance, which in turn can affect the local climate. The sign and magnitude
G. Duveiller+11 more
doaj +1 more source
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar+6 more
wiley +1 more source
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu+7 more
wiley +1 more source