Results 11 to 20 of about 195,628 (75)

From biophysical to integrate-and-fire modelling [PDF]

open access: yesarXiv, 2020
This paper proposes a methodology to extract a low-dimensional integrate-and-fire model from an arbitrarily detailed single-compartment biophysical model. The method aims at relating the modulation of maximal conductance parameters in the biophysical model to the modulation of parameters in the proposed integrate-and-fire model.
arxiv  

A Quantitative Overview of Biophysical Forces Governing Neural Function [PDF]

open access: yes, 2013
The Hodgkin-Huxley (HH) model is the currently accepted formalism of neuronal excitability. However, the HH model does not capture a number of biophysical behaviors associated with action potentials or propagating nerve impulses. Physical mechanisms underlying these processes, such as reversible heat transfer and axonal swelling have been separately ...
arxiv   +1 more source

"The Physics of Life," an undergraduate general education biophysics course [PDF]

open access: yes, 2014
Improving the scientific literacy of non-scientists is an important goal, both because of the ever-increasing impact of science and technology on our lives, and because understanding science enriches our experience of the natural world. One route to improving scientific literacy is via general education undergraduate courses -- i.e.
arxiv   +1 more source

High-throughput design of cultured tissue moulds using a biophysical model [PDF]

open access: yesarXiv, 2023
The technique presented here identifies tethered mould designs, optimised for growing cultured tissue with very highly-aligned cells. It is based on a microscopic biophysical model for polarised cellular hydrogels. There is an unmet need for tools to assist mould and scaffold designs for the growth of cultured tissues with bespoke cell organisations ...
arxiv  

The Twilight of Determinism: At Least in Biophysical Novelties [PDF]

open access: yesarXiv, 2015
In the 1990s, Richard Lewontin referred to what appeared to be the twilight of determinism in biology. He pointed out that DNA determines only a little part of life phenomena, which are very complex. In fact, organisms determine the environment and vice versa in a nonlinear way.
arxiv  

Decomposing multispectral face images into diffuse and specular shading and biophysical parameters [PDF]

open access: yesarXiv, 2019
We propose a novel biophysical and dichromatic reflectance model that efficiently characterises spectral skin reflectance. We show how to fit the model to multispectral face images enabling high quality estimation of diffuse and specular shading as well as biophysical parameter maps (melanin and haemoglobin).
arxiv  

Axonal Computations [PDF]

open access: yesarXiv, 2019
Axons functionally link the somato-dendritic compartment to synaptic terminals. Structurally and functionally diverse, they accomplish a central role in determining the delays and reliability with which neuronal ensembles communicate. By combining their active and passive biophysical properties, they ensure a plethora of physiological computations.
arxiv  

Assessing biophysical and socio-economic impacts of climate change on avian biodiversity [PDF]

open access: yesarXiv, 2020
Climate change threatens biodiversity directly by influencing biophysical variables that drive species' geographic distributions and indirectly through socio-economic changes that influence land use patterns, driven by global consumption, production and climate. To date, no detailed analyses have been produced that assess the relative importance of, or
arxiv  

Emergence of Intrinsic Representations of Images by Feedforward and Feedback Processes and Bioluminescent Photons in Early Retinotopic Areas [PDF]

open access: yesJ Integrative Neuroscience, Vol 10, No. 1, pages 47-64, 2011, 2010
Recently, we put forwarded a redox molecular hypothesis involving the natural biophysical substrate of visual perception and imagery. Here, we explicitly propose that the feedback and feedforward iterative operation processes can be interpreted in terms of a homunculus looking at the biophysical picture in our brain during visual imagery.
arxiv  

An explanation of unexpected Hoxd expressions in mutant mice [PDF]

open access: yesarXiv, 2012
The Hox gene collinearity enigma has often been approached using models based on biomolecular mechanisms. The biophysical model, is an alternative approach, speculating that collinearity is caused by physical forces pulling the Hox clusters from a territory where they are inactive to a distinct spatial domain where they are activated in a step by step ...
arxiv  

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