Results 41 to 50 of about 467,699 (326)

Communications Biophysics [PDF]

open access: yes, 1966
Contains report on one research project.National Institutes of Health (Grant 2 PO1 MH-04737-06)Joint Services Electronics Programs (U.S. Army, U.S. Navy, and U.S.
Sachs, M. B.
core   +3 more sources

Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex

open access: yeseLife, 2016
Nuclear Pore Complexes (NPCs) are key cellular transporter that control nucleocytoplasmic transport in eukaryotic cells, but its transport mechanism is still not understood.
Andrei Vovk   +7 more
doaj   +1 more source

Investigating the potential for a limited quantum speedup on protein lattice problems

open access: yesNew Journal of Physics, 2021
Protein folding is a central challenge in computational biology, with important applications in molecular biology, drug discovery and catalyst design.
Carlos Outeiral   +5 more
doaj   +1 more source

Stage epicrisis: analysis of innovations of the Pavlov University through the eyes of its graduates

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
The article presents a generalized material of the historical establishment of laboratory medicine at the Pavlov First Saint Petersburg State Medical University (University), based on a survey of graduates and employees of the laboratory service of the ...
Yu. V. Emanuel   +3 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Differences in cortical contractile properties between healthy epithelial and cancerous mesenchymal breast cells

open access: yesNew Journal of Physics, 2021
Cell contractility is mainly imagined as a force dipole-like interaction based on actin stress fibers that pull on cellular adhesion sites. Here, we present a different type of contractility based on isotropic contractions within the actomyosin cortex ...
Enrico Warmt   +10 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Communications Biophysics [PDF]

open access: yes, 1965
Contains report on one research project.Joint Services Electronics Program (Contract DA36-039-AMC-03200(E))National Science Foundation (Grant GP-2495)National Institutes of Health (Grant MH-04737-05)National Institutes of Health (Grant 5 RO1 NB-05462-02 ...
Cunningham, A. W. B.   +3 more
core   +6 more sources

Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions

open access: yesCells, 2020
The major defense system against microbial pathogens in vertebrates is the adaptive immune response and represents an effective mechanism in cancer surveillance. T cells represent an essential component of this complex system.
Josephine Alba   +4 more
doaj   +1 more source

Edge-effects dominate copying thermodynamics for finite-length molecular oligomers

open access: yesNew Journal of Physics, 2021
A signature feature of living systems is their ability to produce copies of information-carrying molecular templates such as DNA. These copies are made by assembling a set of monomer molecules into a linear macromolecule with a sequence determined by the
Jenny M Poulton, Thomas E Ouldridge
doaj   +1 more source

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