Results 51 to 60 of about 278,502 (315)
, 2021 Article 13. Biophysics/生物物理学 Author: Liu Huan (1983-), Master of Science (First Class Honours), The University of ...
Liu Huan
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FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
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PathophysiologyThe vagina is an essential component of the female reproductive system and is responsible for providing female sexual satisfaction. Vaginal smooth muscle contraction plays a crucial role in various physiological processes, including sexual arousal ...
Chitaranjan Mahapatra, Ravinder Kumar
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Biophysical Reviews, 2020 My career in science started with my PhD under Professor Darcy Gilmour at the University of Sydney. I quickly learned his iconoclastic ways and completed the degree in early 1969 in just over three years. Professor Charles Birch was the Head of Zoology and had been watching my progress and offered me a position as Lecturer as soon as my PhD was ...
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, 2021 10.1016/j.bbrep.2021.100907Biochemistry and Biophysics ...
Verma, Chandra Shekhar +5 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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STAR ProtocolsSummary: Optogenetic manipulation has proven a powerful tool for investigating the mechanisms underlying the function of neuronal networks, but implementing the technique on mammals during early development remains challenging.
Yu-Nan Chen +3 more
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Journal of Marine Science and Engineering, 2019 Tropical cyclone induced phytoplankton productivity is examined using a tropical cyclone version of the Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS®).
Travis A. Smith +3 more
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, 2011 This editorial celebrates the re-launch of PMC Biophysics previously published by PhysMath Central, in its new format as BMC Biophysics published by BioMed Central with an expanded scope and Editorial Board.
Elizabeth C Moylan
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
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