Results 51 to 60 of about 441,621 (301)

Torque And Optical Traps [PDF]

open access: yes, 2008
Optical traps are an important tool for research in the field of single molecule biophysics. Recent advances in optical trapping have extended their functionality from simple linear manipulation and measurement of forces, to now the ability to rotate ...
Ibeneche, C.
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Biophysical Mechanisms of Vaginal Smooth Muscle Contraction: The Role of the Membrane Potential and Ion Channels

open access: yesPathophysiology
The vagina is an essential component of the female reproductive system and is responsible for providing female sexual satisfaction. Vaginal smooth muscle contraction plays a crucial role in various physiological processes, including sexual arousal ...
Chitaranjan Mahapatra, Ravinder Kumar
doaj   +1 more source

Biophysical Chemistry

open access: yesCHIMIA, 2010
Biophysical chemistry at the Department of Chemistry, University of Basel, covers the NMR analysis of protein–protein interaction using paramagnetic tags and sophisticated microscopy techniques investigating the dynamics of biological matter.
Häussinger, Daniel, Pfohl, Thomas
openaire   +6 more sources

Biophysics of Mechanotransduction [PDF]

open access: yesEuropean Biophysics Journal, 2015
(Singer and Nicolson 1972). As a physical barrier it presents a major target of mechanical forces stretching, compressing, bending or even breaking it, if an excessive force is acting on it. As a composite of a large variety of lipid molecules such as phospholipids, sphingolipids, cholesterol and many others, the lipid bilayer of the cell membrane ...
Boris, Martinac, Andrew R, Battle
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Protocol for adeno-associated virus-mediated optogenetic activation of olfactory output neurons in neonatal mice

open access: yesSTAR Protocols
Summary: Optogenetic manipulation has proven a powerful tool for investigating the mechanisms underlying the function of neuronal networks, but implementing the technique on mammals during early development remains challenging.
Yu-Nan Chen   +3 more
doaj   +1 more source

Biophysical Submesoscale Processes in the Wake of Hurricane Ivan: Simulations and Satellite Observations

open access: yesJournal of Marine Science and Engineering, 2019
Tropical cyclone induced phytoplankton productivity is examined using a tropical cyclone version of the Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS®).
Travis A. Smith   +3 more
doaj   +1 more source

A career in biophysics [PDF]

open access: yesBiophysical Reviews, 2020
My career in science started with my PhD under Professor Darcy Gilmour at the University of Sydney. I quickly learned his iconoclastic ways and completed the degree in early 1969 in just over three years. Professor Charles Birch was the Head of Zoology and had been watching my progress and offered me a position as Lecturer as soon as my PhD was ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy