Results 11 to 20 of about 4,701 (238)

A Mechanistic Insight into the Anti-Staphylococcal Mode of Action of (+)-Usnic Acid and Its Synergy with Norfloxacin Against Methicillin-Resistant Staphylococcus aureus [PDF]

Biomolecules
In this study, a global response analysis was performed to explore the mechanism of action of Usnic acid and its synergy with Norfloxacin, a well-known quinolone antibiotic to which MRSA clinical isolates showed resistance (MIC, 500 µg/mL).
Bhavana Gangwar, Santosh Kumar, Parmanand Kumar, Anirban Pal, Mahendra P. Darokar   +4 more
doaj   +2 more sources

Bioprospection of the Antarctic Diatoms Craspedostauros ineffabilis IMA082A and Craspedostauros zucchelli IMA088A. [PDF]

Mar Drugs
In extreme environments such as Antarctica, a diverse range of organisms, including diatoms, serve as essential reservoirs of distinctive bioactive compounds with significant implications in pharmaceutical, cosmeceutical, nutraceutical, and ...
Trentin R, Moschin E, Custódio L, Moro I.   +3 more
europepmc   +2 more sources

Profiling and cheminformatics bioprospection of curcurbitacin I and momordin Ic from <i>Momordica balsamina</i> on α-amylase and α-glucosidase. [PDF]

J Enzyme Inhib Med Chem
Momordica spp. has been traditionally used to manage type 2 diabetes mellitus, but the mechanisms and metabolites remain unclear. This study evaluated the inhibitory potential of Momordica balsamina extracts on α-amylase and α-glucosidase in vitro ...
Jaichand V, Lanrewaju AA, Baijnath H, Sabiu S, Mohanlall V.   +4 more
europepmc   +2 more sources

Diversity and Bioprospection of Gram-positive Bacteria Derived from a Mayan Sinkhole. [PDF]

Microb Ecol
Water-filled sinkholes known locally as cenotes, found on the Yucatán Peninsula, have remarkable biodiversity. The primary objective of this study was to explore the biotechnological potential of Gram-positive cultivable bacteria obtained from sediment ...
Wissner JL, Parada-Fabián JC, Márquez-Velázquez NA, Escobedo-Hinojosa W, Gaudêncio SP, Prieto-Davó A.   +5 more
europepmc   +2 more sources

Bioprospection of Tenellins Produced by the Entomopathogenic Fungus Beauveria neobassiana. [PDF]

J Fungi (Basel)
Fungi are known as prolific producers of bioactive secondary metabolites with applications across various fields, including infectious diseases, as well as in biological control. However, some of the well-known species are still underexplored.
Toshe R, Charria-Girón E, Khonsanit A, Luangsa-Ard JJ, Khalid SJ, Schrey H, Ebada SS, Stadler M.   +7 more
europepmc   +2 more sources

Correction: Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity [PDF]

Frontiers in Pharmacology
Vidushi Tyagi, Vidushi Tyagi, Ashish Kumar, Karuna Shanker, Anirban Pal, Anirban Pal   +5 more
doaj   +2 more sources

Density functional theory and molecular dynamics simulation-based bioprospection of Agathosma betulina essential oil metabolites against protein tyrosine phosphatase 1B for interventive antidiabetic therapy [PDF]

Heliyon
Adedirin O, Abdulsalam R, Nasir-Naeem K, Oke A, Jubril A, Sabiu S.   +5 more
europepmc   +2 more sources

Bioprospecting Microbial Consortia for Tebuthiuron Degradation in Agricultural Soils: An Alternative Bayesian-Driven Colorimetric Protocol. [PDF]

Environ Microbiol Rep
Microbial consortia from sugarcane soils, particularly ratoon cane environments, showed tebuthiuron‐degrading potential. Bayesian factor estimation of kernel density curves based on logarithmic response ratios enabled interpretation of non‐sigmoidal spectrophotometric data, revealing native microbiota's bioremediation capacity and offering a novel ...
Jorososki LB, Moreira BRA, Cruz VH, Frias YA, Lopes PRM.   +4 more
europepmc   +2 more sources

Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants. [PDF]

Chem Biodivers
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Aruwa CE, Sabiu S.
europepmc   +2 more sources

Les marchés de la biodiversité [PDF]

, 2007
Depuis la fin des années 1980, l’essor des biotechnologies et l’extension des brevets sur le vivant ont laissé entrevoir des possibilités d’utilisations lucratives des substances naturelles, notamment dans les secteurs de la pharmacie, de la cosmétique ...
Aubertin, Catherine, Moretti, Christian
core   +7 more sources