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Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments
Molecular Cancer, 2022 Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy.
S. N. Lone +11 more
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Exosomes as a new frontier of cancer liquid biopsy
Molecular Cancer, 2022 Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and prognosis prediction.
Dan Yu +7 more
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Biology, 2021 Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes.
Roberto Serna-Blasco +6 more
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Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring
Molecular Cancer, 2022 Primary lung cancer is one of the most common malignant tumors in China. Approximately 60% of lung cancer patients have distant metastasis at the initial diagnosis, so it is necessary to find new tumor markers for early diagnosis and individualized ...
Wen Li +18 more
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Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway
Journal of Experimental & Clinical Cancer Research, 2022 Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li +14 more
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Liquid biopsy: current technology and clinical applications
Journal of Hematology & Oncology, 2022 Liquid biopsies are increasingly used for cancer molecular profiling that enables a precision oncology approach. Circulating extracellular nucleic acids (cell-free DNA; cfDNA), circulating tumor DNA (ctDNA), and circulating tumor cells (CTCs) can be ...
M. Nikanjam, S. Kato, R. Kurzrock
semanticscholar +1 more source
Cancer as an infective disease: the role of EVs in tumorigenesis
Molecular Oncology, 2023 Cancer is conventionally considered an evolutionary disease where tumor cells adapt to the environment and evolve eventually leading to the formation of metastasis through the seeding and growth of metastasis‐initiating cells in distant organs.
Lucia Robado de Lope +4 more
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Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway
BMC Cancer, 2021 Background Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful ...
Nana Xu +13 more
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Frontiers in Oncology, 2022 Cancer cells release nucleic acids, freely or associated with other structures such as vesicles into body fluids, including blood. Among these nucleic acids, circulating tumor DNA (ctDNA) has emerged as a minimally invasive biomarker for tumor molecular ...
Estela Sánchez-Herrero +8 more
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Acta Medica Martiniana, 2021 Background: Melanoma is a very heterogeneous human neoplasm. In addition to four major (conventional) histologic subtypes a number of uncommon variants do exist.
Bartos V, Farkasova A.
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