Results 1 to 10 of about 1,974,027 (436)

MRI‐Targeted or Standard Biopsy for Prostate‐Cancer Diagnosis [PDF]

New England Journal of Medicine, 2018
Background Multiparametric magnetic resonance imaging (MRI), with or without targeted biopsy, is an alternative to standard transrectal ultrasonography–guided biopsy for prostate‐cancer detection in men with a raised prostate‐specific antigen level who ...
V. Kasivisvanathan, A. Rannikko, M. Borghi, V. Panebianco, L. Mynderse, M. Vaarala, A. Briganti, L. Budäus, G. Hellawell, R. Hindley, M. Roobol, S. Eggener, M. Ghei, A. Villers, F. Bladou, G. Villeirs, J. Virdi, S. Boxler, G. Robert, Paras Singh, W. Venderink, B. Hadaschik, A. Ruffion, Jim C Hu, D. Margolis, S. Crouzet, L. Klotz, S. Taneja, P. Pinto, I. Gill, C. Allen, F. Giganti, A. Freeman, S. Morris, S. Punwani, N. Williams, C. Brew-Graves, J. Deeks, Y. Takwoingi, M. Emberton, C. Moore   +40 more
semanticscholar   +3 more sources

Prostate biopsies guided by three-dimensional real-time (4-D) transrectal ultrasonography on a phantom: comparative study versus two-dimensional transrectal ultrasound-guided biopsies [PDF]

European Urology 52, 4 (2007) 1097-104, 2007
OBJECTIVE: This study evaluated the accuracy in localisation and distribution of real-time three-dimensional (4-D) ultrasound-guided biopsies on a prostate phantom. METHODS: A prostate phantom was created. A three-dimensional real-time ultrasound system with a 5.9MHz probe was used, making it possible to see several reconstructed orthogonal viewing ...
Alexandre Moreau-Gaudry, Aus, Chen, Chun, Djavan, Epstein, Hodge, Jean-Alexandre Long, Jean-Jacques Rambeaud, Jean-Luc Descotes, Jocelyne Troccaz, Kawakami, Polakow, Ravery, Sauer, Vincent Daanen, Won   +16 more
arxiv   +4 more sources

Prostate Biopsy Assistance System with Gland Deformation Estimation for Enhanced Precision [PDF]

12th International Conference on Medical Imaging and Computer Assisted Intervention, Londres : United Kingdom (2009), 2009
Computer-assisted prostate biopsies became a very active research area during the last years. Prostate tracking makes it possi- ble to overcome several drawbacks of the current standard transrectal ultrasound (TRUS) biopsy procedure, namely the insufficient targeting accuracy which may lead to a biopsy distribution of poor quality, the very approximate
D. Shen, J. Bax, J. Modersitzki, M. Baumann, S. Xu   +4 more
arxiv   +4 more sources

R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies

Biology, 2021
Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes.
Roberto Serna-Blasco, Estela Sánchez-Herrero, María Berrocal Renedo, Silvia Calabuig-Fariñas, Miguel Ángel Molina-Vila, Mariano Provencio, Atocha Romero   +6 more
doaj   +1 more source

Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

Journal of Experimental & Clinical Cancer Research, 2022
Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu, Junqi Liu, Hushan Yang, Shaogui Wan, Yanming Wang, Dengke Bao   +14 more
doaj   +1 more source

Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway

BMC Cancer, 2021
Background Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful ...
Nana Xu, Mengmeng Lu, Jiaxin Wang, Yujia Li, Xiaotian Yang, Xiajie Wei, Jiaoyang Si, Jingru Han, Xiaojuan Yao, Juanmei Zhang, Junqi Liu, Yanming Li, Hushan Yang, Dengke Bao   +13 more
doaj   +1 more source

Cancer as an infective disease: the role of EVs in tumorigenesis

Molecular Oncology, 2023
Cancer is conventionally considered an evolutionary disease where tumor cells adapt to the environment and evolve eventually leading to the formation of metastasis through the seeding and growth of metastasis‐initiating cells in distant organs.
Lucia Robado de Lope, Estela Sánchez‐Herrero, Roberto Serna‐Blasco, Mariano Provencio, Atocha Romero   +4 more
doaj   +1 more source

Circulating Tumor DNA as a Cancer Biomarker: An Overview of Biological Features and Factors That may Impact on ctDNA Analysis

Frontiers in Oncology, 2022
Cancer cells release nucleic acids, freely or associated with other structures such as vesicles into body fluids, including blood. Among these nucleic acids, circulating tumor DNA (ctDNA) has emerged as a minimally invasive biomarker for tumor molecular ...
Estela Sánchez-Herrero, Estela Sánchez-Herrero, Roberto Serna-Blasco, Lucia Robado de Lope, Víctor González-Rumayor, Atocha Romero, Atocha Romero, Mariano Provencio, Mariano Provencio   +8 more
doaj   +1 more source

Liquid Biopsy: From Discovery to Clinical Application.

Cancer Discovery, 2021
Over the past 10 years, circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) have received enormous attention as new biomarkers and subjects of translational research.
C. Alix-Panabières, K. Pantel
semanticscholar   +1 more source

Spindle Cell Melanoma Harboring a Nodule of Epitheloid Cell Melanoma Component: A Study of a Diagnostically Challenging Case

Acta Medica Martiniana, 2021
Background: Melanoma is a very heterogeneous human neoplasm. In addition to four major (conventional) histologic subtypes a number of uncommon variants do exist.
Bartos V, Farkasova A.
doaj   +1 more source