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Application of exosomes as liquid biopsy in clinical diagnosis
Signal Transduction and Targeted Therapy, 2020 Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small extracellular vesicles with sizes between 30–150 nm.
Biting Zhou, Kailun Xu, Xi Zheng
exaly +2 more sources
Comparison of Multiparametric Magnetic Resonance Imaging–Targeted Biopsy With Systematic Transrectal Ultrasonography Biopsy for Biopsy-Naive Men at Risk for Prostate Cancer [PDF]
JAMA Oncology, 2021 Importance Magnetic resonance imaging (MRI) with targeted biopsy is an appealing alternative to systematic 12-core transrectal ultrasonography (TRUS) biopsy for prostate cancer diagnosis, but has yet to be widely adopted. Objective To determine whether
Laurence Klotz +19 more
openalex +2 more sources
Nature Medicine, 2019 During cancer therapy, tumor heterogeneity can drive the evolution of multiple tumor subclones harboring unique resistance mechanisms in an individual patient1–3. Previous case reports and small case series have suggested that liquid biopsy (specifically,
Aparna R Parikh +2 more
exaly +2 more sources
Exosomes as a new frontier of cancer liquid biopsy
Molecular Cancer, 2022 Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and prognosis prediction.
Dan Yu +7 more
semanticscholar +1 more source
Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway
Journal of Experimental & Clinical Cancer Research, 2022 Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li +14 more
doaj +1 more source
Biology, 2021 Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes.
Roberto Serna-Blasco +6 more
doaj +1 more source
Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments
Molecular Cancer, 2022 Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy.
S. N. Lone +11 more
semanticscholar +1 more source
Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring
Molecular Cancer, 2022 Primary lung cancer is one of the most common malignant tumors in China. Approximately 60% of lung cancer patients have distant metastasis at the initial diagnosis, so it is necessary to find new tumor markers for early diagnosis and individualized ...
Wen Li +18 more
semanticscholar +1 more source