Results 131 to 140 of about 1,130,205 (306)

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell‐Targeted Therapies

open access: yesArthritis &Rheumatology, Accepted Article.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no FDA‐approved disease‐modifying therapies for SjD.
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Needle muscle biopsy and its application

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2015
Needle muscle biopsy is a straightforward and reliable minimally-invasive technique. During the past century, the needle biopsy can provide adequate samples and the technique has gradually gained wider acceptance. Compared with open biopsy, needle biopsy
Meng-long CHEN, Cheng ZHANG
doaj  

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

open access: yesCancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan   +11 more
wiley   +1 more source

Is Aortic Balloon Occlusion Effective to Reduce Blood Loss During Lower Lumbar Tumor Resection?

open access: yesCancer Nexus, EarlyView.
ABSTRACT Purpose In this study, we evaluated the efficacy and safety of using an aortic balloon to control blood loss during lower lumbar tumor resection. Methods We retrospectively reviewed 82 patients with tumors involving the lower lumbar spine (L4, L5, or Both), who were treated at our center from July 2015 to September 2023.
Jiacheng Chen   +7 more
wiley   +1 more source

TFE3‐Rearranged PEComa(‐Like Neoplasm) of the Chest Wall Diagnosed by Fine‐Needle Aspiration: A Case Report

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT We report a rare TFE3‐rearranged perivascular epithelioid cell tumor (PEComa) of the parasternal chest wall diagnosed preoperatively by fine‐needle aspiration (FNA) cytology. The smears and cell block showed epithelioid cells with clear to granular cytoplasm and prominent nucleoli.
Shah Dev   +4 more
wiley   +1 more source

Core–Shell Droplet Generation in an On‐Chip Temperature Gradient

open access: yesEuropean Journal of Lipid Science and Technology, EarlyView.
We present a microfluidic device and associated heating–cooling setup for the generation of glycerol monostearate (GMS)‐coated oil droplets. Droplets are generated on‐chip by flow focusing at 60°C, followed by rapid cooling to 6°C. The generated particles range in size from 13 to 49 µm and remain stable for several days at 4°C.
Rui Liu   +4 more
wiley   +1 more source

Medicine‐Food Plant Polysaccharides Modulate Diabetes and Diabetic Complications Through Maintaining Gut Function: A Review

open access: yesFood Frontiers, EarlyView.
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long   +13 more
wiley   +1 more source

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