Results 161 to 170 of about 480,815 (300)

Strain and Shear Wave Elastography in Thyroid Nodules: Tissue Stiffness as a Complementary Risk Marker for Differentiating Benign, Indeterminate, and Malignant Cytology

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the diagnostic performance of shear wave elastography (SWE) and strain elastography (SE) as complementary techniques to conventional B‐mode ultrasound for differentiating benign, indeterminate, and malignant thyroid nodules. Methods This prospective cross‐sectional study included 208 thyroid nodules evaluated using B‐mode
Kairo Alexandre Alves Silveira, Icleia Siqueira Barreto, Ilka Mara Borges Botelho, Elizabeth João Pavin, Ademar Yamanaka, Denise Engelbrecht Zantut‐Wittmann   +5 more
wiley   +1 more source

Toward Objective Anal Cancer Screening: From Swab‐Based Genome‐Wide Methylation Marker Discovery to Novel Test Development

International Journal of Cancer, EarlyView.
ABSTRACT Anal high‐grade squamous intraepithelial lesions (HSIL:AIN2/3) are precursors to anal cancer, and early detection and treatment through screening is crucial for effective cancer prevention. Current guidelines recommend anal swab‐based screening and highlight the need for objective biomarkers to improve risk stratification.
Kirsten Rozemeijer, Jürgen Claesen, Fernando Dias Gonçalves Lima, Albertus T. Hesselink, Phoebe Klingers, Timo ter Braak, Yara van den Burgt, Chris J. L. M. Meijer, Jan M. Prins, Henry J. C. de Vries, Mark A. van de Wiel, Renske D. M. Steenbergen   +11 more
wiley   +1 more source

Gene Expression Biomarkers for Breast Ductal Carcinoma in Situ Recurrence Prediction

International Journal of Cancer, EarlyView.
ABSTRACT Breast ductal carcinoma in situ (DCIS) is often overtreated due to a lack of robust prognostic and predictive tools. This study aimed to evaluate gene expression in a well‐characterised DCIS cohort to determine their clinical utility as biomarkers for ipsilateral recurrence. RNA was extracted from microdissected tissues from primary DCIS.
Alexandria Un, Sakshi Mahale, David Byrne, Dorothea Lesche, Carlos Martinez‐Perez, Jia‐Min Pang, Maree Pechlivanis, Hugo Saunders, Madawa W. Jayawardana, Tongtong Luo, Sureshni I. Jayasinghe, Tanjina Kader, Lisa Devereux, Puay Hoon Tan, Andrew R. Green, Emad A. Rakha, Arran K. Turnbull, Stephen B. Fox, G. Bruce Mann, Kylie L. Gorringe   +19 more
wiley   +1 more source

High acceptability of point‐of‐care HIV testing at the colposcopy outpatient clinic in hospitals in the Netherlands

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 155-162, April 2025.
Abstract Objective Cervical cancer and its precursor are labeled as HIV indicator conditions, justifying the recommendation of HIV testing for all patients. This study aimed to assess the acceptance and patients' and gynecologists' perceptions on HIV testing in patients with cervical dysplasia at the colposcopy outpatient clinic in hospitals in the ...
R. L. O. van de Laar, C. C. E. Jordans, A. Salmaan, W. Hofhuis, S. A. H. M. van den Tillaart, I. A. M. van der Avoort, P. J. Timmers, H. J. van Beekhuizen, H. C. van Doorn, C. Rokx   +9 more
wiley   +1 more source

Minimally Invasive Sampling for Molecular Profiling of Lymph Nodes Using a Modified Acupuncture Needle

iMetaMed, EarlyView.
Schematic illustration of the preparation of His@PDA@Needle, a modified acupuncture needle designed for minimally invasive sampling of lymph node‐derived DNA for molecular profiling. ABSTRACT Current clinical liquid biopsy approaches predominantly rely on blood‐derived biomarkers, which are often limited in sensitivity.
Baiping Cui, Mingyu Li, Pingzhu Zhou, Lihfeng Cheow, Hailong Ma, Dongdong Liu   +5 more
wiley   +1 more source

Endoscopic ultrasound-guided plugged liver biopsy using a fine-needle biopsy needle and coils in patients with deranged coagulation parameters: proof of concept study for feasibility and safety from India. [PDF]

Clin Endosc
Patra BR, Gupta S, Kallurwar Y, Saner C, Harindranath S, Singh A, Vaidya A, Kuruthukulangara M, Yadav J, Lodha G, Pal S, Shukla A.   +11 more
europepmc   +1 more source

Needle muscle biopsy using pleural biopsy needle for diagnosis of inflammatory muscle diseases

, 2005
Background: Inflammatory myopathies are a complex heterogeneous group of disorders in the field of rheumatology. Muscle biopsy is the cornerstone of differential diagnosis.
Forghanizadeh, J., Owlia, M.B.
core  

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Combining biopsy needle and virtual bronchoscopy for tuberculosis-induced complete bronchial blockage. [PDF]

Respirol Case Rep
Nakano Y, Okamoto N, Enomoto Y, Gohma I, Hukuda H, Yamamoto Y, Ikeda N.   +6 more
europepmc   +1 more source

Improving the Accuracy of Papillary Thyroid Cancer Pathological Evaluation With Digital PCR Detection of the BRAF V600E Mutation

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a highly sensitive and specific digital PCR assay for BRAF V600E mutation detection in papillary thyroid cancer (PTC). The increased sensitivity of BRAF mutation detection directly led to more accurate pathological diagnosis of PTC and in turn improved clinical care in patients with limited sample availability or in samples with ...
Na Yu, Kai Zhang, Ying Jiang, Liang Zheng, Xiu He, Qinglin He, Meng Dai, Tianhua Hu, Dongfang Tang, Jingjing Jin, Xin Huang, Li Xiao   +11 more
wiley   +1 more source