Results 171 to 180 of about 1,208,564 (350)

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

Cancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan, Jinsong Xu, Zhanqiao Zhang, Yating Hu, Yongsheng Li, Junying Qian, Yunyan Ling, Dehua Wu, Haijun Deng, Guoxin Li, Zhiyong Shen, Yuan Fang   +11 more
wiley   +1 more source

Needle muscle biopsy and its application

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Needle muscle biopsy is a straightforward and reliable minimally-invasive technique. During the past century, the needle biopsy can provide adequate samples and the technique has gradually gained wider acceptance. Compared with open biopsy, needle biopsy
Meng-long CHEN, Cheng ZHANG
doaj  

Inadvertent arterial & venous injury by bone marrow biopsy needle: case report on rescue embolization techniques. [PDF]

CVIR Endovasc, 2020
Tsai CS, Yu SC.
europepmc   +1 more source

Hydrogel microwells with customizable bottom design: A one‐step approach to spheroid formation

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Conical microwells featuring a variety of bottom‐shape features have received increased recognition because of their enhanced surface characteristics that improve the in vitro‐in vivo correlation in a wide range of biological applications, such as in three‐dimensional cell culture models, specifically cell spheroidal formation, and drug ...
Ahmad A. Manzoor, Omar M. Rahman, Roberto Tarantino, Peter Zastawny, Stephen D. Waldman, Dae Kun Hwang   +5 more
wiley   +1 more source

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

Thyroblastoma in Pregnancy: Expanding the Cytomorphological Spectrum of a Novel DICER1‐Associated Entity, a Case Report and Literature Review

Diagnostic Cytopathology, EarlyView.
ABSTRACT Introduction Thyroblastoma is a rare, aggressive thyroid neoplasm newly classified in the 2022 WHO Classification of Endocrine Tumors. It is characterized by embryonal, multilineage morphology and DICER1 mutations. Fewer than 15 well‐characterized cases have been reported, with limited cytological descriptions.
R. Razack, A. C. van Wyk, P. T. Schubert, D. Pelletier, W. D. Foulkes, C. Njovu, W. Conradie, F. Hoosain   +7 more
wiley   +1 more source

Radial scar on image-guided breast biopsy: Is surgical excision necessary? [PDF]

, 2018
Aft, Rebecca, Chou, Wendy Yen Yun, Veis, Deborah J   +2 more
core   +2 more sources

Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing

Glia, EarlyView.
Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production. ABSTRACT In the hypothalamus, detection of energy substrates such as glucose is essential to regulate ...
Sarah Geller, Nadège Zanou, Sylviane Lagarrigue, Tamara Zehnder, Cathy Gouelle, Tania Santoro, Cendrine Repond, Paola Bezzi, Francesca Amati, Anne‐Karine Bouzier‐Sore, Ariane Sharif, Luc Pellerin   +11 more
wiley   +1 more source

Macrophage Targeting Protects Nerve Structure and Improves Muscle Innervation in a Mouse Model of Charcot‐Marie‐Tooth 2J

Glia, EarlyView.
Hemizygous P0T124M mice develop a late‐onset axonopathy at 18 months of age. Pharmacological macrophage targeting with PLX5622 prevents distal axon degeneration in P0T124M mutant mice and mitigates motor impairment. ABSTRACT In several previous studies, we have shown that macrophage targeting with the CSF‐1 receptor specific kinase (c‐FMS) inhibitor ...
Dennis Klein, Neslim Ercan, Xidi Yuan, Ghjuvan' Ghjacumu Shackleford, Anke Claessens, M. Laura Feltri, Lawrence Wrabetz, Maurizio D'Antonio, Rudolf Martini   +8 more
wiley   +1 more source

Accurate and Minimally Invasive Cervical Pedicle Screw Insertion Procedure Using the Bone Biopsy Needle as Drill Guide. [PDF]

Spine Surg Relat Res, 2020
Koakutsu T, Aizawa T, Itoi E.
europepmc   +1 more source