Results 31 to 40 of about 38,624 (185)

Xenobiotics that affect oxidative phosphorylation alter differentiation of human adipose-derived stem cells at concentrations that are found in human blood

open access: yesDisease Models & Mechanisms, 2015
Adipogenesis is accompanied by differentiation of adipose tissue-derived stem cells to adipocytes. As part of this differentiation, biogenesis of the oxidative phosphorylation system occurs.
Laura Llobet   +4 more
doaj   +1 more source

Herramientas de comunicación en el aprendizaje de la Bioquímica [PDF]

open access: yes, 2017
Sección Deptal. de Bioquímica y Biología Molecular (Biológicas)Depto. de Bioquímica y Biología MolecularFac. de Ciencias BiológicasFac.
Aragonés Sanz, María Dolores   +5 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Molecular and functional characterization of ferredoxin NADP(H) oxidoreductase from Gracilaria chilensis and its complex with ferredoxin

open access: yesBiological Research, 2017
Backgroud Ferredoxin NADP(H) oxidoreductases (EC 1.18.1.2) (FNR) are flavoenzymes present in photosynthetic organisms; they are relevant for the production of reduced donors to redox reactions, i.e.
María Alejandra Vorphal   +7 more
doaj   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

open access: yesAdvanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández   +7 more
wiley   +1 more source

Epitranscriptome changes triggered by ammonium nutrition regulate the proteome response of maritime pine roots

open access: yesFrontiers in Plant Science, 2022
Epitranscriptome constitutes a gene expression checkpoint in all living organisms. Nitrogen is an essential element for plant growth and development that influences gene expression at different levels such as epigenome, transcriptome, proteome, and ...
Francisco Ortigosa   +6 more
doaj   +1 more source

SMARTeaching: Uso de dispositivos móviles en el aula y eficacia de las clases presenciales [PDF]

open access: yes, 2018
Sección Deptal. de Bioquímica y Biología Molecular (Biológicas)Fac.
Feito Castellano, María José   +8 more
core   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet   +5 more
wiley   +1 more source

Neuroinflammation alters cellular proteostasis by producing endoplasmic reticulum stress, autophagy activation and disrupting ERAD activation

open access: yesScientific Reports, 2017
Proteostasis alteration and neuroinflammation are typical features of normal aging. We have previously shown that neuroinflammation alters cellular proteostasis through immunoproteasome induction, leading to a transient decrease of proteasome activity ...
Cristina Pintado   +4 more
doaj   +1 more source

NUAK1 coordinates growth factor-dependent activation of mTORC2 and Akt signaling

open access: yesCell & Bioscience, 2023
Background mTORC2 is a critical regulator of cytoskeleton organization, cell proliferation, and cancer cell survival. Activated mTORC2 induces maximal activation of Akt by phosphorylation of Ser-473, but regulation of Akt activity and signaling crosstalk
Mario Palma   +9 more
doaj   +1 more source

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