Results 281 to 290 of about 182,780 (336)

Biotechnical Multiscale Engineering of Scaffolds for Stem Cell and Organoid Research

open access: yesSmall, EarlyView.
Biotechnical multiscale engineering consideration of geometric and structural parameters, which is called biotechnical multiscale engineering, has an influence on stem cell development and organogenesis comparable to that of molecular genetics and biochemical parameters.
Merle‐Johanna Küstner   +13 more
wiley   +1 more source

Corneal Nerve Regeneration via MSC‐Derived EVs: Tissue Source and Culture Dimensionality Dictate miRNA Cargo and Therapeutic Efficacy

open access: yesSmall, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) from human cornea and bone marrow, cultured in 2D and 3D conditions, are characterized and tested for corneal nerve repair. 3D‐derived EVs show superior therapeutic efficacy and in vivo reinnervation.
Hamed Massoumi   +17 more
wiley   +1 more source

Cell Culture Substrate Variation Alters Extracellular Vesicle Biogenesis Without Affecting Non‐Coding Repeat RNA Profile

open access: yesSmall, EarlyView.
Cell culture biomechanical conditions influence extracellular vesicles (EVs) production in patient‐derived pancreatic adenocarcinoma (PDAC) cell lines. When grown in 3D conformation and in hydrogels with lower elasticity (0.5kPA), PDAC cells produce higher numbers of EVs, compared with cells grown in 2D on classic cell culture plastic.
Sara I. Veiga   +9 more
wiley   +1 more source

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