Results 261 to 270 of about 185,824 (352)

Innovative methodology for flexible monitoring of various bioprocesses by using pre‐existing Raman data coupled with automated transfer learning technique

Biotechnology Progress, EarlyView.
The application of the transfer learning algorithm successfully allowed the use of a model built on process A for real‐time monitoring of process B. This study shows the improvement obtained with this methodology compared to the direct application of the model.
Adèle Schini, Hadi El Radi, Johan Cailletaud, Célia Sanchez, Nathan Gay, Bruno Ebel, Emmanuel Guedon, Laurent Jourdainne   +7 more
wiley   +1 more source

Blue LED-assisted bioreactor cultivation enhances carotenoid accumulation in Rhodotorula mucilaginosa LB-01. [PDF]

Appl Microbiol Biotechnol
Delgado Cuadros AL, Ortiz Silos N, Garcia Bustos K, Tejada Meza K, Colina Andrade G, Terán Hilares R.   +5 more
europepmc   +1 more source

Pilot Plant Studies of Single Sludge Nitrogen Removal of Night Soil Using U-Tube Bioreactor.

, 1996
Hiroshi Ishida, Yutaka Yamada, Kiyoshi Izumi, Masashi Moro, Takane KITAO   +4 more
openalex   +2 more sources

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Modeling and validating of oxygen transport in wave bioreactors: optimized experimental mass transfer method and novel Lattice-Boltzmann CFD approach. [PDF]

Front Bioeng Biotechnol
Piontek S, Fitschen J, Weiland C, Habicher T, Schlüter M, Wucherpfennig T.   +5 more
europepmc   +1 more source

Rapid development of a transferable Raman model using high‐throughput cell culture for monitoring monoclonal antibody titer

Biotechnology Progress, EarlyView.
Abstract Monoclonal antibody (mAb) titer monitoring is a key capability during process development and optimization, enabling timely decision making and increasing the speed of development. Raman spectroscopy is a prominent process analytical technology (PAT), but resource‐efficient calibration strategies for the development of transferable models are ...
Alexandra Umprecht, Nicholas Uth, Haenah Kim, Oliver Spadiut, Yang Yang   +4 more
wiley   +1 more source

Imperatives for anaerobic high cell density culturing by denitrification: technical and physiological perspectives. [PDF]

Microb Cell Fact
Maråk MM, Duister IM, Bakken LR, Bergaust LL.   +3 more
europepmc   +1 more source

Bioreactor

Sen'i Gakkaishi, 1991
openaire   +2 more sources

On‐deck pH measurement with integrated feedback control on a micro‐scale platform for monoclonal antibody low pH viral inactivation

Biotechnology Progress, EarlyView.
Integrating an automated, on‐deck pH measurement method with feedback control enables precise, real‐time pH adjustment during low pH viral inactivation on a micro‐scale platform. Abstract The increasing demand for efficient monoclonal antibody manufacturing has accelerated the adoption of high throughput process development (HTPD) platforms, which ...
Paras Sharma, Nikolas von den Eichen, Sabine Schweisgut, Lars Robbel, Michael Schmitt, Daniel G. Bracewell   +5 more
wiley   +1 more source

A unique blend of five human milk oligosaccharides supports recovery of infant microbiome composition and function after <i>ex vivo</i> antibiotic use. [PDF]

Front Pediatr
Morrin ST, Buck RH, Hill DR.
europepmc   +1 more source