Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience. [PDF]
Dettmer R +4 more
europepmc +1 more source
Abstract The objective of this work is to demonstrate that the inclusion of an up‐flow anaerobic sludge bed (UASB reactor) within an industrial wastewater treatment plant reduces the plant's investment and operating costs compared to a system based solely on conventional complete‐mix activated sludge (CMAS), operating under the same design principles ...
Juan Manuel Morgan‐Sagastume +1 more
wiley +1 more source
Review of CFD modelling techniques for single‐phase and multiphase flow in static mixers
This review synthesizes computational fluid dynamics (CFD) approaches for static mixers, linking hydrodynamics to pressure drop, particle/droplet distributions, mixing metrics, and heat‐transfer performance to guide modelling choices and design decisions. Abstract Static mixers enable compact and low‐energy intensification.
Jussan Jaeger +7 more
wiley +1 more source
Systematic pathway engineering of Escherichia coli for enhanced 3'-sialyllactose production. [PDF]
Wu Y +8 more
europepmc +1 more source
Romidepsin (RMD), an FDA‐approved histone deacetylase inhibitor for treating cancer, demonstrates potent latency‐reversing activity in vitro but has yielded suboptimal outcomes in kick‐and‐kill HIV‐cure trials when administered as a 5 mg/m2 infusion.
Lauren A. R. Tompkins +7 more
wiley +1 more source
Microfluidic production of monodisperse food‐additive polymer capsules for biological applications
Monodisperse TGPR polymer capsules are generated via a robust microfluidic approach exploiting droplet interface transfer across the oil‒water interface. Unlike lipid vesicles, these capsules offer high thermal stability and biocompatibility. They successfully demonstrated utility as robust bioreactors for in‐capsule PCR and bacterial cultivation ...
Yuki Gondo +5 more
wiley +1 more source
Continuous autotrophic production of alcohols with Clostridium autoethanogenum LAbrini in a submerged membrane bioreactor. [PDF]
Oppelt A +4 more
europepmc +1 more source
Challenges in Implementing European Regulation on Water Reuse for Sustainable Agriculture
ABSTRACT The Regulation (EU) 2020/741 on minimum requirements for water reuse is a key policy for sustainable water management under growing water scarcity in Europe. This paper examines expert perspectives on the challenges involved in implementing EU regulation for water reuse in agriculture, aiming to broaden existing research, which is largely ...
Patricia Allgaier +2 more
wiley +1 more source
High-solids ethanol production from waste paper through consolidated bioprocessing using advanced Saccharomyces cerevisiae strains. [PDF]
Naudé JE +3 more
europepmc +1 more source
Lentiviral vector purification using QA CIM monolith anion‐exchange chromatography was optimized via 96‐well and DOE, increasing recovery from 20% to 90%. The process achieved 3.3‐log host cell protein reduction, decreased particle impurities, and showed high binding capacity, supporting large‐scale manufacturing.
Luka Bevc +7 more
wiley +1 more source

