This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang +13 more
wiley +1 more source
Evolutionary Adaptation and Targeted Metabolic Engineering Synergistically Improve Methanol-Derived Single-Cell Protein Production in Pichia pastoris. [PDF]
Xie C +6 more
europepmc +1 more source
Integrated cellulase continuous production and downstream processing using a packed-bed bioreactor for solid-state fermentation by thermophilic fungus. [PDF]
Mafra NSC, Casciatori FP.
europepmc +1 more source
High-cell density two-stage self-cycling fermentation system for the enhanced production of ethanol from steam-exploded poplar hydrolysate. [PDF]
Hung YR, Bressler DC, Sauvageau D.
europepmc +1 more source
Oxygen-based soft-sensing of glucose demand in Chinese hamster ovary fed-batch cultures across scales. [PDF]
Jossen V +4 more
europepmc +1 more source
Acetate to caproate: metagenomic insights into functional shifts in a methane-arrested anaerobic bioreactor. [PDF]
Schaerer LG +3 more
europepmc +1 more source
Optimisation and Scale-Up of the Heterologous Production of the Antifungal Protein PeAfpA From Penicillium expansum in Stirred-Tank Bioreactors. [PDF]
de Ovalle S +6 more
europepmc +1 more source

