Results 61 to 70 of about 6,069,719 (250)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

STIRRED BIOREACTOR FOR THE ROBUSTNESS PRODUCTION OF RECOMBINANT GST.VP28 IN FED-BATCH CULTIVATION OF ESCHERICHIA COLI

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2015
Escherichia coli is the most popular platform for the production of recombinant proteins as vaccine candidates. One important factor that may influence the quantity and quality of the expressed proteins using the bacterial host is a bioreactor.
MUHAMAD ALI , ISMAINI, SULAIMAN N. DEPAMEDE, BAGUS D. H. SETYONO, ALIS MUKHLIS, MUHAMAD AMIN, MOHAMMAD ASHARI   +6 more
doaj  

Extracellular expression, purification and bioreactor production of tambaqui (Colossoma macropomum) growth hormone in the yeast Komagataella phaffii (formerly Pichia pastoris) [PDF]

Acta Amazonica
Due to its zootechnical importance, the gene encoding growth hormone (GH) from several fish species has been isolated and expressed in heterologous systems.
Elson Antonio SADALLA-PINTO, Edmar de ANDRADE, Edson Junior do CARMO, Júlio Nino de SOUZA-NETO, Larissa Matos BATISTA, Alexandra Regina BENTES-SOUSA, Luis André Morais MARIÚBA, Douglas de França PASSOS, Rodrigo Pimentel FERNANDES, Nei PEREIRA JUNIOR, Jorge Ivan Rebelo PORTO, Spartaco ASTOLFI-FILHO   +11 more
doaj   +1 more source

Xylose metabolism in the fungus Rhizopus oryzae : effect of growth and respiration on l (+)-lactic acid production [PDF]

, 2008
The fungus Rhizopus oryzae converts both glucose and xylose under aerobic conditions into chirally pure l(+)-lactic acid with by-products such as xylitol, glycerol, ethanol, carbon dioxide and fungal biomass.
Eggink, G., Ronald H. W. Maas, Springer, J., Weusthuis, R.A., Ruud A. Weusthuis, Maas, R.H.W., Gerrit Eggink, Jan Springer   +7 more
core   +1 more source

Transforming Brain Organoids Into Functional Platforms: Convergence of Engineering, Imaging, AI, and Ethics

Advanced Science, EarlyView.
Brain organoids are emerging as increasingly functional human‐relevant platforms, yet limitations in vascularization, maturation, measurement, and reproducibility still constrain their translational value. This Perspective examines how microfluidics, biofabrication, advanced imaging, electrophysiology, multimodal AI, standardization, and ethical ...
Aishwarya Pantula, Kaustubh Joshi, Swarangi Samant, Greta Babakhanova, Annie Kathuria   +4 more
wiley   +1 more source

Scale up of Xylanase Production by Submerged Fermentation from Brevibacillus Borstelentis (MTCC 9874) and Digestibility Assessment of Crude Xylanase in Wheat.

SVU-International Journal of Veterinary Sciences, 2019
The main objective of this study was to scale up xylanase production from isolated soil microbe (Brevibacillus borselensis; the Microbial Type Culture Collection (MTCC) 9874) in a bioreactor and check digestibility of this crude enzyme in animal feed ...
Milan Phuyal, Shristi Joshi, Alisha Pradhan, Roshani Rokaya, Saniya Shrestha, Uttam Budhathoki   +5 more
doaj   +1 more source

Optimization of process variables for acetoin production in a bioreactor using Taguchi orthogonal array design

Heliyon, 2020
Microbial production of acetoin is eco-friendly and inexpensive when compared with its synthetic methods of production. In the present findings, bioproduction of acetoin in a typical bioreactor was discussed with a view to ascertain the seemingly ...
Abiola Ezekiel Taiwo, Tafirenyika Nyamayaro Madzimbamuto, Tunde Victor Ojumu   +2 more
doaj   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Three-Stage Anaerobic Sequencing Batch Reactor (ASBR) for Maximum Methane Production: Effects of COD Loading Rate and Reactor Volumetric Ratio

Energies, 2018
A three-stage anaerobic sequencing batch reactor system was developed as a new anaerobic process with an emphasis on methane production from ethanol wastewater.
Achiraya Jiraprasertwong, Kornpong Vichaitanapat, Malinee Leethochawalit, Sumaeth Chavadej   +3 more
doaj   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source