Catabolic mobile genetic elements and their potential use in bioaugmentation of polluted soils and waters [PDF]
Boon, Nico, SPRINGAEL, D, TOP, EM
core +1 more source
The power of many: when genetics met yeasts and high‐throughput
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Miniature bioreactor arrays for modeling functional and structural dysbiosis in inflammatory bowel disease. [PDF]
Newman KL +9 more
europepmc +1 more source
ABSTRACT Many firms set ambitious sustainability goals but these are frequently “displaced” by proxy goals that are easier to track and measure. However, the specific types of goal conflicts that follow from this displacement are poorly understood. We conducted a case study of circular innovation initiatives at a global MedTech company and identified ...
Wiebke Reim +2 more
wiley +1 more source
Autotrophic and Mixotrophic Batch Processes with Clostridium autoethanogenum LAbrini in Stirred Tank Bioreactors with Continuous Gassing. [PDF]
Oppelt A +3 more
europepmc +1 more source
Effect of cell retention techniques in Komagataella phaffii lab‐scale continuous processes
Abstract Perfusion technologies play a growing role in the implementation of continuous processes for biotherapeutics production in mammalian‐based manufacturing. However, their application to alternative production hosts is limited. Cell retention systems are of key importance for the efficiency of perfusion bioreactors.
Marina Y. Linova +5 more
wiley +1 more source
Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya +7 more
wiley +1 more source
Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation. [PDF]
Springuel P +14 more
europepmc +1 more source
Abstract Scaled production of cultivated meat (CM) will co‐produce large volumes of spent media. Recycling of abundant metabolites such as lactic acid in spent media offers an opportunity for valorization and reduction of the carbon footprint of CM production; however, the feasibility has yet to be examined.
Josh Wimble +2 more
wiley +1 more source
A unique blend of five human milk oligosaccharides supports recovery of infant microbiome composition and function after <i>ex vivo</i> antibiotic use. [PDF]
Morrin ST, Buck RH, Hill DR.
europepmc +1 more source

